Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	glx
Name .....................................................	:	Glyoxylate, etc.Glyoxalate, Glyoxylic acid
Model ID .....................................................	:	C00048
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00048
Formula .....................................................	:	C2H1O3
Charge .....................................................	:	-1
Localization .....................................................	:	Extracellular, Cytosol, Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	glx
Other associations .....................................................	:	See reaction table below (11 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Represented in 5 maps... Alanine metabolism (c,m) Glycine and threonine metabolism (c,m) Glyoxylate and dicarboxylate metabolism (c,m) Proline metabolism (c,m) TCA cycle (m)   Go to map

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00369Name: L-Alanine:glyoxylate aminotransferase Type: Regular Location: Cytosol KEGG ID: R00369 click to see details on this item	2.6.1.44Name: alanine---glyoxylate transaminase Other names: AGT, alanine-glyoxylate aminotransferase, alanine-glyoxylic aminotransferase, L-alanine-glycine transaminase click to see details on this item	[c] : ala-LName: L-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item		glyName: Glycine Formula: C2H5NO2 Charge: 0 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item	T09B4.8 | agxt-1	Alanine metabolism
RM00369Name: L-Alanine:glyoxylate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R00369 click to see details on this item	2.6.1.44Name: alanine---glyoxylate transaminase Other names: AGT, alanine-glyoxylate aminotransferase, alanine-glyoxylic aminotransferase, L-alanine-glycine transaminase click to see details on this item	[m] : ala-LName: L-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item		glyName: Glycine Formula: C2H5NO2 Charge: 0 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item	T09B4.8 | agxt-1	Alanine metabolism
RM00471Name: D-4-Hydroxy-2-oxoglutarate glyoxylate-lyase Type: Regular Location: Mitochondria KEGG ID: R00471 click to see details on this item	4.1.3.16Name: 4-hydroxy-2-oxoglutarate aldolase Other names: 2-oxo-4-hydroxyglutarate aldolase, hydroxyketoglutaric aldolase, 4-hydroxy-2-ketoglutaric aldolase, 2-keto-4-hydroxyglutaric aldolase, 4-hydroxy-2-ketoglutarate aldolase, 2-keto-4-hydroxyglutarate aldolase, 2-oxo-4-hydroxyglutaric aldolase, DL-4-hydroxy-2-ketoglutarate aldolase, hydroxyketoglutarate aldolase, 2-keto-4-hydroxybutyrate aldolase, 4-hydroxy-2-oxoglutarate glyoxylate-lyase, KHGA click to see details on this item	[m] : 4h2ogltName: 4-Hydroxy-2-oxoglutarate Formula: C5H4O6 Charge: -2 click to see details on this item		glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item	Unknown	Proline metabolism
RC00471Name: D-4-Hydroxy-2-oxoglutarate glyoxylate-lyase Type: Regular Location: Cytosol KEGG ID: R00471 click to see details on this item	4.1.3.16Name: 4-hydroxy-2-oxoglutarate aldolase Other names: 2-oxo-4-hydroxyglutarate aldolase, hydroxyketoglutaric aldolase, 4-hydroxy-2-ketoglutaric aldolase, 2-keto-4-hydroxyglutaric aldolase, 4-hydroxy-2-ketoglutarate aldolase, 2-keto-4-hydroxyglutarate aldolase, 2-oxo-4-hydroxyglutaric aldolase, DL-4-hydroxy-2-ketoglutarate aldolase, hydroxyketoglutarate aldolase, 2-keto-4-hydroxybutyrate aldolase, 4-hydroxy-2-oxoglutarate glyoxylate-lyase, KHGA click to see details on this item	[c] : 4h2ogltName: 4-Hydroxy-2-oxoglutarate Formula: C5H4O6 Charge: -2 click to see details on this item		glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item	Unknown	Proline metabolism
RC00366Name: glycine:oxygen oxidoreductase (deaminating) Type: Regular Location: Cytosol KEGG ID: R00366 click to see details on this item	1.4.3.3Name: D-amino-acid oxidase Other names: ophio-amino-acid oxidase, L-amino acid:O2 oxidoreductase, new yellow enzyme click to see details on this item	[c] : glyName: Glycine Formula: C2H5NO2 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	daao-1	Glycine and threonine metabolism
RC00475Name: Glycolate:oxygen 2-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00475 click to see details on this item	1.1.3.15Name: (S)-2-hydroxy-acid oxidase Other names: hydroxy-acid oxidase A, hydroxy-acid oxidase B, glycolate oxidase, L-2-hydroxy acid oxidase, hydroxyacid oxidase A, L-alpha-hydroxy acid oxidase click to see details on this item	[c] : glycltName: Glycolate Formula: C2H3O3 Charge: -1 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item	F41E6.5	Glyoxylate and dicarboxylate metabolism
RM00472Name: malate synthase Type: Regular Location: Mitochondria KEGG ID: R00472 click to see details on this item	2.3.3.9Name: malate synthase Other names: L-malate glyoxylate-lyase (CoA-acetylating), glyoxylate transacetylase, glyoxylate transacetase, glyoxylic transacetase, malate condensing enzyme, malate synthetase, malic synthetase, malic-condensing enzyme click to see details on this item	[m] : accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + mal-LName: L-Malate Formula: C4H4O5 Charge: -2 click to see details on this item	icl-1	Glyoxylate and dicarboxylate metabolism
RM00479Name: isocitrate lyase Type: Regular Location: Mitochondria KEGG ID: R00479 click to see details on this item	4.1.3.1Name: isocitrate lyase Other names: isocitrase, isocitritase, isocitratase, threo-Ds-isocitrate glyoxylate-lyase, isocitrate glyoxylate-lyase click to see details on this item	[m] : icitName: Isocitrate Formula: C6H5O7 Charge: -3 click to see details on this item		glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item	icl-1	Glyoxylate and dicarboxylate metabolism
TCE5371Name: Glyoxylate transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item[c]		glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item[e]	Not determined	Transport
TCM0183Name: Glyoxylate transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item[c]		glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item[m]	Not determined	Transport
EX00048Name: Glyoxylate exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	glxName: Glyoxylate Formula: C2H1O3 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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