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Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Metabolite Overview
Abbreviation ..................................................... : orot
Name ..................................................... : Orotate, etc.Orotic acid, Uracil-6-carboxylic acid
Model ID ..................................................... : C00295
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : C00295
Formula ..................................................... : C5H3N2O4
Charge ..................................................... : -1
Localization ..................................................... : Extracellular, Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : orot
Other associations ..................................................... : See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Pyrimidine metabolism (c)
Comments
ERROR
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RM01868Name: (S)-dihydroorotate:quinone oxidoreductase
Type: Regular
Location: Cytosol, Mitochondria
KEGG ID: R01868

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1.3.5.2Name: dihydroorotate dehydrogenase (quinone)
Other names: dihydroorotate:ubiquinone oxidoreductase, (S)-dihydroorotate:(acceptor) oxidoreductase, (S)-dihydroorotate:acceptor oxidoreductase, DHOdehase (ambiguous), DHOD (ambiguous), DHODase (ambiguous), DHODH

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dhor-SName: (S)-Dihydroorotate
Formula: C5H5N2O4
Charge: -1




click to see details on this item[c] + qName: Ubiquinone
Formula: C14H18O4
Charge: 0




click to see details on this item[m]
orotName: Orotate
Formula: C5H3N2O4
Charge: -1




click to see details on this item[c] + qh2Name: Ubiquinol
Formula: C14H20O4
Charge: 0




click to see details on this item[m]
dhod-1
Pyrimidine metabolism
RC01870Name: Orotidine-5-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase
Type: Regular
Location: Cytosol
KEGG ID: R01870

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2.4.2.10Name: orotate phosphoribosyltransferase
Other names: orotidylic acid phosphorylase, orotidine-5'-phosphate pyrophosphorylase, OPRTase, orotate phosphoribosyl pyrophosphate transferase, orotic acid phosphoribosyltransferase, orotidine 5'-monophosphate pyrophosphorylase, orotidine monophosphate pyrophosphorylase, orotidine phosphoribosyltransferase, orotidylate phosphoribosyltransferase, orotidylate pyrophosphorylase, orotidylic acid pyrophosphorylase, orotidylic phosphorylase, orotidylic pyrophosphorylase

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[c] : orot5pName: Orotidine 5'-phosphate
Formula: C10H10N2O11P
Charge: -3




click to see details on this item + ppiName: Diphosphate
Formula: HO7P2
Charge: -3




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orotName: Orotate
Formula: C5H3N2O4
Charge: -1




click to see details on this item + prppName: 5-Phospho-alpha-D-ribose 1-diphosphate
Formula: C5H8O14P3
Charge: -5




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R12E2.11 | umps-1
Pyrimidine metabolism
TCE5348Name: Orotate transport
Type: Transport
Location: Cytosol, Extracellular
KEGG ID: NA

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Not applicable
orotName: Orotate
Formula: C5H3N2O4
Charge: -1




click to see details on this item[e]
orotName: Orotate
Formula: C5H3N2O4
Charge: -1




click to see details on this item[c]
Not determined
Transport
EX00295Name: Orotate exchange
Type: Exchange
Location: Extracellular
KEGG ID: NA

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Not applicable
orotName: Orotate
Formula: C5H3N2O4
Charge: -1




click to see details on this item[e]
Not applicable
Exchange with the environment
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