Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	srtn
Name .....................................................	:	Serotonin, etc.3-(2-Aminoethyl)-1H-indol-5-ol, 5-Hydroxytryptamine, Enteramine
Model ID .....................................................	:	C00780
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00780
Formula .....................................................	:	C10H13N2O
Charge .....................................................	:	+1
Localization .....................................................	:	Extracellular, Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	srtn
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Tryptophan degradation (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC02908Name: 5-Hydroxytryptamine:oxygen oxidoreductase (deaminating) (flavin-containing) Type: Regular Location: Cytosol KEGG ID: R02908 click to see details on this item	1.4.3.4Name: monoamine oxidase Other names: adrenalin oxidase, adrenaline oxidase, amine oxidase (ambiguous), amine oxidase (flavin-containing), amine:oxygen oxidoreductase (deaminating) (flavin-containing), epinephrine oxidase, MAO, MAO A, MAO B, MAO-A, MAO-B, monoamine oxidase A, monoamine oxidase B, monoamine:O2 oxidoreductase (deaminating), polyamine oxidase (ambiguous), serotonin deaminase, spermidine oxidase (ambiguous), spermine oxidase (ambiguous), tyraminase, tyramine oxidase click to see details on this item	[c] : srtnName: Serotonin Formula: C10H13N2O Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		5hoxindactName: 5-Hydroxyindoleacetaldehyde Formula: C10H9NO2 Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item	amx-2	Tryptophan degradation
RC02701Name: 5-Hydroxy-L-tryptophan decarboxy-lyase Type: Regular Location: Cytosol KEGG ID: R02701 click to see details on this item	4.1.1.28Name: aromatic-L-amino-acid decarboxylase Other names: DOPA decarboxylase, tryptophan decarboxylase, hydroxytryptophan decarboxylase, L-DOPA decarboxylase, aromatic amino acid decarboxylase, 5-hydroxytryptophan decarboxylase, aromatic-L-amino-acid carboxy-lyase (tryptamine-forming) click to see details on this item	[c] : 5htrpName: 5-Hydroxy-L-tryptophan Formula: C11H12N2O3 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		srtnName: Serotonin Formula: C10H13N2O Charge: 1 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	bas-1	Tryptophan degradation
TCE5113Name: Secretion of serotonin Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	srtnName: Serotonin Formula: C10H13N2O Charge: 1 click to see details on this item[c] + atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c] + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item[c]		srtnName: Serotonin Formula: C10H13N2O Charge: 1 click to see details on this item[e] + adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[c] + hName: H+ Formula: H Charge: 1 click to see details on this item[c] + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item[c]	cat-1	Transport
TCE5114Name: Uptake of serotonin Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	srtnName: Serotonin Formula: C10H13N2O Charge: 1 click to see details on this item[e]		srtnName: Serotonin Formula: C10H13N2O Charge: 1 click to see details on this item[c]	Not determined	Transport
EX00780Name: Serotonin exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	srtnName: Serotonin Formula: C10H13N2O Charge: 1 click to see details on this item[e]			Not applicable	Exchange with the environment

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