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  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 2.3.1.61
Name ..................................................... : Dihydrolipoyllysine-residue succinyltransferase, etc.Dihydrolipoamide S-succinyltransferase, Dihydrolipoamide succinyltransferase, Dihydrolipoic transsuccinylase, Dihydrolipolyl transsuccinylase, Dihydrolipoyl transsuccinylase, Lipoate succinyltransferase (Escherichia coli), Lipoic transsuccinylase, Lipoyl transsuccinylase, Succinyl-CoA:dihydrolipoamide S-succinyltransferase, Succinyl-CoA:dihydrolipoate S-succinyltransferase, Enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00658DLST sucB; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
Genes ..................................................... : dlst-1
Localization ..................................................... : Mitochondria
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RMC0003Name: 2-oxoglutarate dehydrogenase
Type: Regular
Location: Mitochondria
KEGG ID: R00621;R03316;R02570;R07618

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1.2.4.2Name: oxoglutarate dehydrogenase (succinyl-transferring)
Other names: 2-ketoglutarate dehydrogenase, 2-oxoglutarate dehydrogenase, 2-oxoglutarate: lipoate oxidoreductase, 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating), alpha-ketoglutarate dehydrogenase, alphaketoglutaric acid dehydrogenase, alpha-ketoglutaric dehydrogenase, alpha-oxoglutarate dehydrogenase, AKGDH, OGDC, ketoglutaric dehydrogenase, oxoglutarate decarboxylase, oxoglutarate dehydrogenase, oxoglutarate dehydrogenase (lipoamide)

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2.3.1.61Name: dihydrolipoyllysine-residue succinyltransferase
Other names: dihydrolipoamide S-succinyltransferase, dihydrolipoamide succinyltransferase, dihydrolipoic transsuccinylase, dihydrolipolyl transsuccinylase, dihydrolipoyl transsuccinylase, lipoate succinyltransferase (Escherichia coli), lipoic transsuccinylase, lipoyl transsuccinylase, succinyl-CoA:dihydrolipoamide S-succinyltransferase, succinyl-CoA:dihydrolipoate S-succinyltransferase, enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase

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1.8.1.4Name: dihydrolipoyl dehydrogenase
Other names: LDP-Glc, LDP-Val, dehydrolipoate dehydrogenase, diaphorase, dihydrolipoamide dehydrogenase, dihydrolipoamide:NAD+ oxidoreductase, dihydrolipoic dehydrogenase, dihydrothioctic dehydrogenase, lipoamide dehydrogenase (NADH), lipoamide oxidoreductase (NADH), lipoamide reductase, lipoamide reductase (NADH), lipoate dehydrogenase, lipoic acid dehydrogenase, lipoyl dehydrogenase, protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase

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[m] : akgName: 2-Oxoglutarate
Formula: C5H4O5
Charge: -2




click to see details on this item + coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




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co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




click to see details on this item + succoaName: Succinyl-CoA
Formula: C25H35N7O19P3S
Charge: -5




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(ogdh-1 & ogdh-2) & dlst-1 & dld-1
TCA cycle
RMC0014Name: 2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating); Glutaryl-CoA:dihydrolipoamide S-succinyltransferase; Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
Type: Regular
Location: Mitochondria
KEGG ID: R01940;R02571;R07618

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1.2.4.2Name: oxoglutarate dehydrogenase (succinyl-transferring)
Other names: 2-ketoglutarate dehydrogenase, 2-oxoglutarate dehydrogenase, 2-oxoglutarate: lipoate oxidoreductase, 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating), alpha-ketoglutarate dehydrogenase, alphaketoglutaric acid dehydrogenase, alpha-ketoglutaric dehydrogenase, alpha-oxoglutarate dehydrogenase, AKGDH, OGDC, ketoglutaric dehydrogenase, oxoglutarate decarboxylase, oxoglutarate dehydrogenase, oxoglutarate dehydrogenase (lipoamide)

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2.3.1.61Name: dihydrolipoyllysine-residue succinyltransferase
Other names: dihydrolipoamide S-succinyltransferase, dihydrolipoamide succinyltransferase, dihydrolipoic transsuccinylase, dihydrolipolyl transsuccinylase, dihydrolipoyl transsuccinylase, lipoate succinyltransferase (Escherichia coli), lipoic transsuccinylase, lipoyl transsuccinylase, succinyl-CoA:dihydrolipoamide S-succinyltransferase, succinyl-CoA:dihydrolipoate S-succinyltransferase, enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase

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1.8.1.4Name: dihydrolipoyl dehydrogenase
Other names: LDP-Glc, LDP-Val, dehydrolipoate dehydrogenase, diaphorase, dihydrolipoamide dehydrogenase, dihydrolipoamide:NAD+ oxidoreductase, dihydrolipoic dehydrogenase, dihydrothioctic dehydrogenase, lipoamide dehydrogenase (NADH), lipoamide oxidoreductase (NADH), lipoamide reductase, lipoamide reductase (NADH), lipoate dehydrogenase, lipoic acid dehydrogenase, lipoyl dehydrogenase, protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase

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[m] : 2oxoadpName: 2-Oxoadipate
Formula: C6H6O5
Charge: -2




click to see details on this item + coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




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co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item + glutcoaName: Glutaryl-CoA
Formula: C26H37N7O19P3S
Charge: -5




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




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(ogdh-1 & ogdh-2) & dlst-1 & dld-1
Lysine degradation
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