WormFlux: mechanistic analysis of C. elegans metabolism

(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	4.4.1.1
Name .....................................................	:	Cystathionine gamma-lyase, etc.Homoserine deaminase, Homoserine dehydratase, Cystine desulfhydrase, Cysteine desulfhydrase, Gamma-cystathionase, Cystathionase, Homoserine deaminase-cystathionase, Gamma-CTL, Cystalysin, Cysteine lyase, L-cystathionine cysteine-lyase (deaminating)
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K01758CTH; cystathionine gamma-lyase [EC:4.4.1.1]
Genes .....................................................	:	cbl-1, cth-1, cth-2
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below.

External links

KEGG

BRENDA

Reactions

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00782Name: L-Cysteine hydrogen-sulfide-lyase (deaminating, pyruvate-forming) Type: Regular Location: Cytosol KEGG ID: R00782 click to see details on this item	4.4.1.1Name: cystathionine gamma-lyase Other names: homoserine deaminase, homoserine dehydratase, cystine desulfhydrase, cysteine desulfhydrase, gamma-cystathionase, cystathionase, homoserine deaminase-cystathionase, gamma-CTL, cystalysin, cysteine lyase, L-cystathionine cysteine-lyase (deaminating) click to see details on this item	[c] : cys-LName: L-Cysteine Formula: C3H7NO2S Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	h2sName: Hydrogen sulfide Formula: H2S Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item	cbl-1 \| cth-1 \| cth-2	Cysteine metabolism
RC01001Name: L-cystathionine cysteine-lyase (deaminating, 2-oxobutanoate-forming) Type: Regular Location: Cytosol KEGG ID: R01001 click to see details on this item	4.4.1.1Name: cystathionine gamma-lyase Other names: homoserine deaminase, homoserine dehydratase, cystine desulfhydrase, cysteine desulfhydrase, gamma-cystathionase, cystathionase, homoserine deaminase-cystathionase, gamma-CTL, cystalysin, cysteine lyase, L-cystathionine cysteine-lyase (deaminating) click to see details on this item	[c] : cyst-LName: L-Cystathionine Formula: C7H14N2O4S Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	2obutName: 2-Oxobutanoate Formula: C4H5O3 Charge: -1 click to see details on this item + cys-LName: L-Cysteine Formula: C3H7NO2S Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	cbl-1 \| cth-1 \| cth-2	Cysteine metabolism
RC04770Name: Selenomethionine methanethiol-lyase (deaminating) Type: Regular Location: Cytosol KEGG ID: R04770 click to see details on this item	4.4.1.1Name: cystathionine gamma-lyase Other names: homoserine deaminase, homoserine dehydratase, cystine desulfhydrase, cysteine desulfhydrase, gamma-cystathionase, cystathionase, homoserine deaminase-cystathionase, gamma-CTL, cystalysin, cysteine lyase, L-cystathionine cysteine-lyase (deaminating) click to see details on this item	[c] : selmethName: Selenomethionine Formula: C5H11NO2Se Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	metselName: Methylselenol Formula: CH3Se Charge: -1 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + 2obutName: 2-Oxobutanoate Formula: C4H5O3 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	cbl-1 \| cth-1 \| cth-2	Selenocompound metabolism

The information and tools provided in this website are to be used for academic purposes only. Potential users of the flux analysis tools (FBA button in the vertical menu) are asked to show proof of working at an academic institution during the creation of their accounts. These mathematical tools are powered by the commercial software Gurobi.