Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	chol
Name .....................................................	:	Choline, etc.Bilineurine
Model ID .....................................................	:	C00114
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00114
Formula .....................................................	:	C5H14NO
Charge .....................................................	:	+1
Localization .....................................................	:	Extracellular, Cytosol, Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	chol
Other associations .....................................................	:	See reaction table below (10 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Glycerophospholipid metabolism (c,m), Serine metabolism (c,m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01310Name: Phosphatidylcholine phosphatidohydrolase Type: Regular Location: Cytosol KEGG ID: R01310 click to see details on this item	3.1.4.4Name: phospholipase D Other names: lipophosphodiesterase II, lecithinase D, choline phosphatase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + pcholName: Phosphatidylcholine Formula: C8H18NO4PFULLRCO2FULLR2CO2 Charge: 0 click to see details on this item		cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + pa_plName: Phosphatidic acid (phospholipids) Formula: C3H5O4PFULLRCO2FULLR2CO2 Charge: -2 click to see details on this item	pld-1 | (F09G2.8 | T05C3.6 | Y51A2D.13)	Glycerophospholipid metabolism
RC01030Name: sn-Glycero-3-phosphocholine glycerophosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01030 click to see details on this item	3.1.4.46Name: glycerophosphodiester phosphodiesterase Other names: gene hpd protein, glycerophosphoryl diester phosphodiesterase, IgD-binding protein D click to see details on this item	[c] : g3pcName: sn-Glycero-3-phosphocholine Formula: C8H20NO6P Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item + glyc3pName: Glycerol 3-phosphate Formula: C3H7O6P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	T12B3.3 | T22G5.1 | ZC155.4	Glycerophospholipid metabolism
RC01023Name: Acetyl-CoA:choline O-acetyltransferase Type: Regular Location: Cytosol KEGG ID: R01023 click to see details on this item	2.3.1.6Name: choline O-acetyltransferase Other names: choline acetylase, choline acetyltransferase click to see details on this item	[c] : accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item		achName: Acetylcholine Formula: C7H16NO2 Charge: 1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item	cha-1	Glycerophospholipid metabolism
RC01026Name: Acetylcholine aectylhydrolase Type: Regular Location: Cytosol KEGG ID: R01026 click to see details on this item	3.1.1.7Name: acetylcholinesterase Other names: true cholinesterase, choline esterase I, cholinesterase, acetylthiocholinesterase, acetylcholine hydrolase, acetyl.beta-methylcholinesterase, AcCholE click to see details on this item	[c] : achName: Acetylcholine Formula: C7H16NO2 Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	ace-1 | ace-2 | ace-4	Glycerophospholipid metabolism
RC01021Name: ATP:choline phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01021 click to see details on this item	2.7.1.32Name: choline kinase Other names: choline kinase (phosphorylating), choline phosphokinase, choline-ethanolamine kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + cholpName: Choline phosphate Formula: C5H13NO4P Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	(cka-1 | cka-2 | ckb-1 | ckb-2 | ckb-3) | ckb-4	Glycerophospholipid metabolism
RC07377Name: phosphatidylserine synthase 1 Type: Regular Location: Cytosol KEGG ID: R07377 click to see details on this item	2.7.8.-Name: phosphatidylserine synthase 1 Other names: cDP-diacylglycerol:phosphatidylglycerol 3-phosphatidyltransferase click to see details on this item	[c] : pcholName: Phosphatidylcholine Formula: C8H18NO4PFULLRCO2FULLR2CO2 Charge: 0 click to see details on this item + ser-LName: L-Serine Formula: C3H7NO3 Charge: 0 click to see details on this item		cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item + psName: Phosphatidylserine Formula: C6H11NO6PFULLRCO2FULLR2CO2 Charge: -1 click to see details on this item	pssy-1	Glycerophospholipid metabolism
RM01025Name: choline:acceptor 1-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R01025 click to see details on this item	1.1.99.1Name: choline dehydrogenase Other names: choline oxidase, choline-cytochrome c reductase, choline:(acceptor) oxidoreductase, choline:(acceptor) 1-oxidoreductase click to see details on this item	[m] : cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item + fadName: Flavin adenine dinucleotide oxidized Formula: C27H31N9O15P2 Charge: -2 click to see details on this item		betaldName: Betaine aldehyde Formula: C5H12NO Charge: 1 click to see details on this item + fadh2Name: Flavin adenine dinucleotide reduced Formula: C27H33N9O15P2 Charge: -2 click to see details on this item	C34C6.4	Glycerophospholipid metabolism
TCM0196Name: Choline transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item[c]		cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item[m]	Not determined	Transport
TCE0757Name: Choline transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item[e]		cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item[c]	Not determined	Transport
EX00114Name: Choline exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	cholName: Choline Formula: C5H14NO Charge: 1 click to see details on this item[e]			Not applicable	Exchange with the environment

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