Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	arachd
Name .....................................................	:	arachidonic acid, etc.Arachidonate, (5Z,8Z,11Z,14Z)-Icosatetraenoic acid, cis-5,8,11,14-Eicosatetraenoic acid
Model ID .....................................................	:	C00219
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00219
Formula .....................................................	:	C20H31O2
Charge .....................................................	:	-1
Localization .....................................................	:	Extracellular, Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	arachd
Other associations .....................................................	:	See reaction table below (7 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Fatty acid biosynthesis (c,e)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01595Name: Arachidonate:oxygen 5-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01595 click to see details on this item	1.13.11.34Name: arachidonate 5-lipoxygenase Other names: leukotriene-A4 synthase, Delta5-lipoxygenase, 5Delta-lipoxygenase, arachidonic 5-lipoxygenase, arachidonic acid 5-lipoxygenase, C-5-lipoxygenase, LTA synthase, leukotriene A4 synthase click to see details on this item	[c] : arachdName: arachidonic acid Formula: C20H31O2 Charge: -1 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		5HPETName: "5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate" Formula: C20H31O4 Charge: -1 click to see details on this item	To be determined	Arachidonic acid metabolism
RC07041Name: Arachidonic acid:oxygen 1-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R07041 click to see details on this item	1.14.15.3Name: alkane 1-monooxygenase Other names: alkane 1-hydroxylase, omega-hydroxylase, fatty acid omega-hydroxylase, alkane monooxygenase, 1-hydroxylase, alkane hydroxylase click to see details on this item	[c] : arachdName: arachidonic acid Formula: C20H31O2 Charge: -1 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		20HETEName: 20-Hydroxyeicosatetraenoic acid Formula: C20H31O3 Charge: -1 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	cyp-37A1 | cyp-37B1	Arachidonic acid metabolism
RCC0078Name: Prostaglandin G/H synthase Type: Regular Location: Cytosol KEGG ID: R01590;R00073 click to see details on this item	1.14.99.1Name: prostaglandin-endoperoxide synthase Other names: prostaglandin synthase, prostaglandin G/H synthase, (PG)H synthase, PG synthetase, prostaglandin synthetase, fatty acid cyclooxygenase, prostaglandin endoperoxide synthetase click to see details on this item	[c] : arachdName: arachidonic acid Formula: C20H31O2 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (2) o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + prostgh2Name: Prostaglandin H2 Formula: C20H31O5 Charge: -1 click to see details on this item	To be determined	Arachidonic acid metabolism
RC07050Name: aryl hydrocarbon hydroxylase Type: Regular Location: Cytosol KEGG ID: R07050 click to see details on this item	1.14.14.1Name: unspecific monooxygenase Other names: microsomal monooxygenase, xenobiotic monooxygenase, aryl-4-monooxygenase, aryl hydrocarbon hydroxylase, microsomal P-450, flavoprotein-linked monooxygenase, flavoprotein monooxygenase click to see details on this item	[c] : o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + arachdName: arachidonic acid Formula: C20H31O2 Charge: -1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + eetName: 11,12-EET Formula: C20H31O3 Charge: -1 click to see details on this item	cyp-35A1 | cyp-35A2 | cyp-35A4 | cyp-35A5	Arachidonic acid metabolism
RC08183Name: Archidonyl-CoA thioesterase Type: Regular Location: Cytosol KEGG ID: R08183 click to see details on this item	3.1.2.2Name: palmitoyl-CoA hydrolase Other names: long-chain fatty-acyl-CoA hydrolase, palmitoyl coenzyme A hydrolase, palmitoyl thioesterase, palmitoyl coenzyme A hydrolase, palmitoyl-CoA deacylase, palmityl thioesterase, palmityl-CoA deacylase, fatty acyl thioesterase I, palmityl thioesterase I click to see details on this item	[c] : arachdcoaName: C20:4-CoA Formula: C41H62N7O17P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		arachdName: arachidonic acid Formula: C20H31O2 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	K05B2.4 | (W03D8.8 | T05E7.1) | C31H5.6 | (C17C3.1 | C17C3.3 | C37H5.13 | F25E2.3)	Fatty acid biosynthesis
TCE0352Name: arachidonic acid transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	arachdName: arachidonic acid Formula: C20H31O2 Charge: -1 click to see details on this item[e]		arachdName: arachidonic acid Formula: C20H31O2 Charge: -1 click to see details on this item[c]	Not determined	Transport
EX00219Name: arachidonic acid exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	arachdName: arachidonic acid Formula: C20H31O2 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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