Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	hdca
Name .....................................................	:	Hexadecanoate (n-C16:0), etc.Hexadecanoic acid, Hexadecanoate, Hexadecylic acid, Palmitic acid, Palmitate, Cetylic acid
Model ID .....................................................	:	C00249
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00249
Formula .....................................................	:	C16H31O2
Charge .....................................................	:	-1
Localization .....................................................	:	Extracellular, Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	hdca
Other associations .....................................................	:	See reaction table below (7 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Fatty acid biosynthesis (c), Retinol metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0020Name: fatty acid synthetase (palmitate, n-C16:0) Type: Regular Location: Cytosol KEGG ID: R05188 click to see details on this item	2.3.1.85Name: fatty-acid synthase Other names: FASN (gene name) click to see details on this item	[c] : accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + (20) hName: H+ Formula: H Charge: 1 click to see details on this item + (7) malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (14) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		(7) co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + (8) coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (6) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + hdcaName: Hexadecanoate (n-C16:0) Formula: C16H31O2 Charge: -1 click to see details on this item + (14) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	fasn-1	Fatty acid biosynthesis
RC01274Name: Palmitoyl-CoA hydrolase Type: Regular Location: Cytosol KEGG ID: R01274 click to see details on this item	3.1.2.22Name: palmitoyl[protein] hydrolase Other names: palmitoyl-protein thioesterase, palmitoyl-(protein) hydrolase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + pmtcoaName: Palmitoyl-CoA (n-C16:0CoA) Formula: C37H62N7O17P3S Charge: -4 click to see details on this item		coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + hdcaName: Hexadecanoate (n-C16:0) Formula: C16H31O2 Charge: -1 click to see details on this item	ppt-1	Fatty acid biosynthesis
RC01280Name: Palmitate:CoA ligase (AMP-forming) Type: Regular Location: Cytosol KEGG ID: R01280 click to see details on this item	6.2.1.3Name: long-chain-fatty-acid---CoA ligase Other names: acyl-CoA synthetase, fatty acid thiokinase (long chain), acyl-activating enzyme, palmitoyl-CoA synthase, lignoceroyl-CoA synthase, arachidonyl-CoA synthetase, acyl coenzyme A synthetase, acyl-CoA ligase, palmitoyl coenzyme A synthetase, thiokinase, palmitoyl-CoA ligase, acyl-coenzyme A ligase, fatty acid CoA ligase, long-chain fatty acyl coenzyme A synthetase, oleoyl-CoA synthetase, stearoyl-CoA synthetase, long chain fatty acyl-CoA synthetase, long-chain acyl CoA synthetase, fatty acid elongase, LCFA synthetase, pristanoyl-CoA synthetase, ACS3, long-chain acyl-CoA synthetase I, long-chain acyl-CoA synthetase II, fatty acyl-coenzyme A synthetase, long-chain acyl-coenzyme A synthetase, FAA1 click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hdcaName: Hexadecanoate (n-C16:0) Formula: C16H31O2 Charge: -1 click to see details on this item		ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + pmtcoaName: Palmitoyl-CoA (n-C16:0CoA) Formula: C37H62N7O17P3S Charge: -4 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	acs-2 | acs-3 | acs-4 | acs-5 | acs-13 | acs-15 | acs-17 | acs-18	Fatty acid biosynthesis
RC08388Name: all-trans-retinyl ester acylhydrolase, 11-cis-retinol forming Type: Regular Location: Cytosol KEGG ID: R08388 click to see details on this item	3.1.1.64Name: retinoid isomerohydrolase Other names: all-trans-retinyl-palmitate hydrolase (ambiguous), retinol isomerase (ambiguous), all-trans-retinol isomerase:hydrolase (ambiguous), all-trans-retinylester 11-cis isomerohydrolase, RPE65 (gene name) click to see details on this item	[c] : retpalmName: Retinyl palminate Formula: C36H60O2 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		retinol-cis-11Name: cis-11-retinol Formula: C20H30O Charge: 0 click to see details on this item + hdcaName: Hexadecanoate (n-C16:0) Formula: C16H31O2 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	bcmo-2	Retinol metabolism
DGR0004Name: Bacterial fatty acid composition Type: Degradation Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	[c] : Rtotal_BACName: R total from bacterial diet Formula: RCO2 Charge: -1 click to see details on this item		(0.056282) ttdcaName: tetradecanoate (n-C14:0) Formula: C14H27O2 Charge: -1 click to see details on this item + (0.430027) hdcaName: Hexadecanoate (n-C16:0) Formula: C16H31O2 Charge: -1 click to see details on this item + (0.042082) fa16p1n7Name: Palmitoleic acid Formula: C16H29O2 Charge: -1 click to see details on this item + (0.311026) fa17c9Name: cis-9,10-methylenehexadecanoic acid Formula: C17H31O2 Charge: -1 click to see details on this item + (0.065863) fa19c11Name: cis-11,12-methyleneoctadecanoic acid Formula: C19H35O2 Charge: -1 click to see details on this item + (0.09472) vaccName: Vaccenic acid Formula: C18H33O2 Charge: -1 click to see details on this item	Not applicable	Bacterial digestion
TCE0329Name: Hexadecanoate (n-C16:0) transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	hdcaName: Hexadecanoate (n-C16:0) Formula: C16H31O2 Charge: -1 click to see details on this item[e]		hdcaName: Hexadecanoate (n-C16:0) Formula: C16H31O2 Charge: -1 click to see details on this item[c]	Not determined	Transport
EX00249Name: Hexadecanoate (n-C16:0) exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	hdcaName: Hexadecanoate (n-C16:0) Formula: C16H31O2 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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