HOME DOWNLOAD CITATION HELP
Umass Logo PSB Logo
(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Metabolite Overview
Abbreviation ..................................................... : paf
Name ..................................................... : Platelet-activating factor, etc.2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine, PAF
Model ID ..................................................... : C04598
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : C04598
Formula ..................................................... : C10H21NO7PRC2H4
Charge ..................................................... : 0
Localization ..................................................... : Extracellular, Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : Not available
Other associations ..................................................... : See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Ether lipid metabolism (c)
Comments
  • Charge based on human version in BiGG.

    • Reactions
    ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

    I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
    & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

    If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.     		Pathway
    RC04321Name: CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase
    Type: Regular
    Location: Cytosol
    KEGG ID: R04321

    click to see details on this item
    2.7.8.2Name: diacylglycerol cholinephosphotransferase
    Other names: phosphorylcholine-glyceride transferase, alkylacylglycerol cholinephosphotransferase, 1-alkyl-2-acetylglycerol cholinephosphotransferase, cholinephosphotransferase, CPT, alkylacylglycerol choline phosphotransferase, diacylglycerol choline phosphotransferase, 1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase, CDP-choline diglyceride phosphotransferase, cytidine diphosphocholine glyceride transferase, cytidine diphosphorylcholine diglyceride transferase, phosphocholine diacylglyceroltransferase, sn-1,2-diacylglycerol cholinephosphotransferase, 1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase, CDP choline:1,2-diacylglycerol cholinephosphotransferase, CDP-choline:1,2-diacylglycerol cholinephosphotransferase

    click to see details on this item
    [c] : cdpcholName: CDPcholine
    Formula: C14H25N4O11P2
    Charge: -1




    click to see details on this item     + acakgName: 2-Acetyl-1-alkyl-sn-glycerol
    Formula: C5H9O4RC2H4
    Charge: 0




    click to see details on this item
    cmpName: CMP
    Formula: C9H12N3O8P
    Charge: -2




    click to see details on this item     + pafName: Platelet-activating factor
    Formula: C10H21NO7PRC2H4
    Charge: 0




    click to see details on this item     + hName: H+
    Formula: H
    Charge: 1




    click to see details on this item
    cept-2
    Ether lipid metabolism
    RC04452Name: Platelet-activating factor acetylhydrolase
    Type: Regular
    Location: Cytosol
    KEGG ID: R04452

    click to see details on this item
    3.1.1.47Name: 1-alkyl-2-acetylglycerophosphocholine esterase
    Other names: 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase, alkylacetyl-GPC:acetylhydrolase

    click to see details on this item
    [c] : pafName: Platelet-activating factor
    Formula: C10H21NO7PRC2H4
    Charge: 0




    click to see details on this item     + h2oName: H2O
    Formula: H2O
    Charge: 0




    click to see details on this item
    ak2lgcholName: 1-Alkyl-2-lyso-sn-glycero-3-phosphocholine
    Formula: C8H19NO6PRC2H4
    Charge: 0




    click to see details on this item     + acName: Acetate
    Formula: C2H3O2
    Charge: -1




    click to see details on this item     + hName: H+
    Formula: H
    Charge: 1




    click to see details on this item
    [(paf-1 | paf-2) | C27A7.5] | lis-1
    Ether lipid metabolism
    TCE5384Name: Platelet-activating factor secretion
    Type: Transport
    Location: Cytosol, Extracellular
    KEGG ID: NA

    click to see details on this item
    Not applicable
    atpName: ATP
    Formula: C10H12N5O13P3
    Charge: -4




    click to see details on this item    [c] + h2oName: H2O
    Formula: H2O
    Charge: 0




    click to see details on this item    [c] + pafName: Platelet-activating factor
    Formula: C10H21NO7PRC2H4
    Charge: 0




    click to see details on this item    [c]
    adpName: ADP
    Formula: C10H12N5O10P2
    Charge: -3




    click to see details on this item    [c] + hName: H+
    Formula: H
    Charge: 1




    click to see details on this item    [c] + pafName: Platelet-activating factor
    Formula: C10H21NO7PRC2H4
    Charge: 0




    click to see details on this item    [e] + piName: Phosphate
    Formula: HO4P
    Charge: -2




    click to see details on this item    [c]
    Not determined
    Transport
    TCE5385Name: Platelet-activating factor uptake
    Type: Transport
    Location: Cytosol, Extracellular
    KEGG ID: NA

    click to see details on this item
    Not applicable
    pafName: Platelet-activating factor
    Formula: C10H21NO7PRC2H4
    Charge: 0




    click to see details on this item    [e]
    pafName: Platelet-activating factor
    Formula: C10H21NO7PRC2H4
    Charge: 0




    click to see details on this item    [c]
    Not determined
    Transport
    EX04598Name: Platelet-activating factor exchange
    Type: Exchange
    Location: Extracellular
    KEGG ID: NA

    click to see details on this item
    Not applicable
    pafName: Platelet-activating factor
    Formula: C10H21NO7PRC2H4
    Charge: 0




    click to see details on this item    [e]
    Not applicable
    Exchange with the environment
    The information and tools provided in this website are to be used for academic purposes only. Potential users of the flux analysis tools (FBA button in the vertical menu) are asked to show proof of working at an academic institution during the creation of their accounts. These mathematical tools are powered by the commercial software Gurobi.