Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	3hmp
Name .....................................................	:	3-Hydroxy-2-methylpropanoate, etc.(S)-3-Hydroxyisobutyrate
Model ID .....................................................	:	C06001
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C06001
Formula .....................................................	:	C4H7O3
Charge .....................................................	:	-1
Localization .....................................................	:	Extracellular, Cytosol, Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	3hmp
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Valine degradation (m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM05064Name: (S)-3-Hydroxyisobutyryl-CoA hydrolase Type: Regular Location: Mitochondria KEGG ID: R05064 click to see details on this item	3.1.2.4Name: 3-hydroxyisobutyryl-CoA hydrolase Other names: 3-hydroxy-isobutyryl CoA hydrolase, HIB CoA deacylase click to see details on this item	[m] : 3hibutcoaName: (S)-3-Hydroxyisobutyryl-CoA Formula: C25H38N7O18P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		3hmpName: 3-Hydroxy-2-methylpropanoate Formula: C4H7O3 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hach-1	Valine degradation
RM05066Name: 3-Hydroxy-2-methylpropanoate:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R05066 click to see details on this item	1.1.1.31Name: 3-hydroxyisobutyrate dehydrogenase Other names: beta-hydroxyisobutyrate dehydrogenase click to see details on this item 1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item	[m] : 3hmpName: 3-Hydroxy-2-methylpropanoate Formula: C4H7O3 Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		2mopName: 2-Methyl-3-oxopropanoate Formula: C4H5O3 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	B0250.5 | (B0272.3 | F54C8.1 | ech-8 | ech-9 | hacd-1)	Valine degradation
TCE5364Name: 3-Hydroxy-2-methylpropanoate transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	3hmpName: 3-Hydroxy-2-methylpropanoate Formula: C4H7O3 Charge: -1 click to see details on this item[c]		3hmpName: 3-Hydroxy-2-methylpropanoate Formula: C4H7O3 Charge: -1 click to see details on this item[e]	Not determined	Transport
EX06001Name: 3-Hydroxy-2-methylpropanoate exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	3hmpName: 3-Hydroxy-2-methylpropanoate Formula: C4H7O3 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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