HOME DOWNLOAD CITATION HELP
Umass Logo PSB Logo
(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Metabolite Overview
Abbreviation ..................................................... : 7a3o4chlstnt
Name ..................................................... : 7alpha-Hydroxy-3-oxo-4-cholestenoate
Model ID ..................................................... : C17337
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : C17337
Formula ..................................................... : C27H41O4
Charge ..................................................... : -1
Localization ..................................................... : Extracellular, Cytosol, Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : Not available
Other associations ..................................................... : See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Biosynthesis of bile acid-like molecules (c,e,m)
Comments
  • Charge based on another bile acid with a very similar structure, cholate.

    • Reactions
    ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

    I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
    & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

    If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.     		Pathway
    RC08725Name: 7alpha,26-dihydroxy-4-cholesten-3-one,NADPH:oxygen oxidoreductase (26-hydroxylating)
    Type: Regular
    Location: Cytosol
    KEGG ID: R08725

    click to see details on this item
    1.14.13.15Name: cholestanetriol 26-monooxygenase
    Other names: 5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase, 5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase, cholestanetriol 26-hydroxylase, sterol 27-hydroxylase, sterol 26-hydroxylase, cholesterol 27-hydroxylase, CYP27A, CYP27A1, cytochrome P450 27A1'

    click to see details on this item
    [c] : xol27oneName: 7alpha,26-Dihydroxy-4-cholesten-3-one
    Formula: C27H44O3
    Charge: 0




    click to see details on this item     + hName: H+
    Formula: H
    Charge: 1




    click to see details on this item     + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
    Formula: C21H26N7O17P3
    Charge: -4




    click to see details on this item     + (2) o2Name: O2
    Formula: O2
    Charge: 0




    click to see details on this item
    (3) h2oName: H2O
    Formula: H2O
    Charge: 0




    click to see details on this item     + (2) nadpName: Nicotinamide adenine dinucleotide phosphate
    Formula: C21H25N7O17P3
    Charge: -3




    click to see details on this item     + 7a3o4chlstntName: 7alpha-Hydroxy-3-oxo-4-cholestenoate
    Formula: C27H41O4
    Charge: -1




    click to see details on this item
    daf-9
    Biosynthesis of bile acid-like molecules
    TCE5040Name: cholestenoate transport
    Type: Transport
    Location: Cytosol, Extracellular
    KEGG ID: NA

    click to see details on this item
    Not applicable
    7a3o4chlstntName: 7alpha-Hydroxy-3-oxo-4-cholestenoate
    Formula: C27H41O4
    Charge: -1




    click to see details on this item    [e]
    7a3o4chlstntName: 7alpha-Hydroxy-3-oxo-4-cholestenoate
    Formula: C27H41O4
    Charge: -1




    click to see details on this item    [c]
    Not determined
    Transport
    TCM5040Name: cholestenoate transport (cytosol/mitochondria)
    Type: Transport
    Location: Cytosol, Mitochondria
    KEGG ID: NA

    click to see details on this item
    Not applicable
    7a3o4chlstntName: 7alpha-Hydroxy-3-oxo-4-cholestenoate
    Formula: C27H41O4
    Charge: -1




    click to see details on this item    [c]
    7a3o4chlstntName: 7alpha-Hydroxy-3-oxo-4-cholestenoate
    Formula: C27H41O4
    Charge: -1




    click to see details on this item    [m]
    Not determined
    Transport
    EX17337Name: 7alpha-Hydroxy-3-oxo-4-cholestenoate exchange
    Type: Exchange
    Location: Extracellular
    KEGG ID: NA

    click to see details on this item
    Not applicable
    7a3o4chlstntName: 7alpha-Hydroxy-3-oxo-4-cholestenoate
    Formula: C27H41O4
    Charge: -1




    click to see details on this item    [e]
    Not applicable
    Exchange with the environment
    The information and tools provided in this website are to be used for academic purposes only. Potential users of the flux analysis tools (FBA button in the vertical menu) are asked to show proof of working at an academic institution during the creation of their accounts. These mathematical tools are powered by the commercial software Gurobi.