WormFlux: mechanistic analysis of C. elegans metabolism

Metabolite Overview

Abbreviation .....................................................	:	protSfar
Name .....................................................	:	S-Farnesyl protein, etc.S-Farnesyl protein C-terminal CAAX
Model ID .....................................................	:	C20120
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C20120
Formula .....................................................	:	C20H33N2O3SR(C2H2NOR)n(C2H2NOR)n
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	Not available
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Not yet represented in WormPaths maps.

iCEL1314

Comments

Formula adjusted to a system where peptide account is consistent with reaction balancing.

(C2H2NOR)n represents the repetitive peptide, first group in the C terminal, second in the N terminal.

The sign would depend on the protein but taken zero by convention.

Reactions

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC09844Name: farnesyl-diphosphate:protein-cysteine farnesyltransferase Type: Regular Location: Cytosol KEGG ID: R09844 click to see details on this item	2.5.1.58Name: protein farnesyltransferase Other names: FTase click to see details on this item	[c] : frdpName: Farnesyl diphosphate Formula: C15H25O7P2 Charge: -3 click to see details on this item + protCysName: Protein-cysteine Formula: C5H9N2O3SR(C2H2NOR)n(C2H2NOR)n Charge: 0 click to see details on this item	protSfarName: S-Farnesyl protein Formula: C20H33N2O3SR(C2H2NOR)n(C2H2NOR)n Charge: 0 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	fntb-1 & fnta-1	Miscellaneous
RC09845Name: prenyl protein peptidase; Ste24 endopeptidase (acting on farnesyl moiety) Type: Regular Location: Cytosol KEGG ID: R09845 click to see details on this item	3.4.24.84Name: Ste24 endopeptidase click to see details on this item 3.4.22.-Name: prenyl protein peptidase Other names: Ste24 endopeptidase (acting on geranyl-geranyl moiety), prenyl protein peptidase, Ste24 endopeptidase (acting on farnesyl moiety) click to see details on this item	[c] : protSfarName: S-Farnesyl protein Formula: C20H33N2O3SR(C2H2NOR)n(C2H2NOR)n Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	protSfarCName: Protein C-terminal S-farnesyl-L-cysteine Formula: C20H33N2O3SR(C2H2NOR)n Charge: 0 click to see details on this item + pepdName: Peptide Formula: C2H4NO2R(C2H2NOR)n Charge: 0 click to see details on this item	fce-1 \| fce-2	Miscellaneous
BIO0015Name: Assembly of minor components of biomass Type: Biomass Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	protSfarName: S-Farnesyl protein Formula: C20H33N2O3SR(C2H2NOR)n(C2H2NOR)n Charge: 0 click to see details on this item[c] + protSgerCName: Protein C-terminal S-geranylgeranyl-L-cysteine Formula: C25H41N2O3SR(C2H2NOR)n Charge: 0 click to see details on this item[c] + hemeproteinName: Hemeprotein Formula: C34H30FeN4O4X Charge: 0 click to see details on this item[c] + protSfarCmetName: Protein C-terminal S-farnesyl-L-cysteine methyl ester Formula: C21H35N2O3SR(C2H2NOR)n Charge: 0 click to see details on this item[c] + protSgerName: S-geranylgeranyl protein Formula: C25H41N2O3SR(C2H2NOR)n(C2H2NOR)n Charge: 0 click to see details on this item[c] + (4.0) pepdName: Peptide Formula: C2H4NO2R(C2H2NOR)n Charge: 0 click to see details on this item[c] + protSfarCName: Protein C-terminal S-farnesyl-L-cysteine Formula: C20H33N2O3SR(C2H2NOR)n Charge: 0 click to see details on this item[c] + focytCName: Ferrocytochrome C Formula: C42H42FeN8O8S2R4 Charge: 0 click to see details on this item[m] + protSgerCmetName: Protein C-terminal S-geranylgeranyl-L-cysteine methyl ester Formula: C26H43N2O3SR(C2H2NOR)n Charge: 0 click to see details on this item[c] + ISclustprotName: Iron-sulfur cluster protein Formula: XFe2S2 Charge: 6 click to see details on this item[m]	biomass_minorName: Minor components of biomass Formula: X Charge: 0 click to see details on this item[c] + apoISclustprotName: apo iron-sulfur cluster protein Formula: X Charge: 0 click to see details on this item[m] + apocytcName: Apo cytochrome C Formula: C8H12N4O4S2R4 Charge: 0 click to see details on this item[m] + apohemeproteinName: Apohemeprotein Formula: X Charge: 0 click to see details on this item[c] + (6.0) protCysName: Protein-cysteine Formula: C5H9N2O3SR(C2H2NOR)n(C2H2NOR)n Charge: 0 click to see details on this item[c]	Not applicable	Biomass assembly

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