HOME DOWNLOAD CITATION HELP
Umass Logo PSB Logo
(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.1.1.181
Name ..................................................... : Cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase, etc.3beta-hydroxy-Delta5-C27-steroid oxidoreductase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : Not determined
Genes ..................................................... : hsd-1, hsd-2, hsd-3
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC04262Name: 3beta-hydroxy-Delta5-C27-steroid oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R04263

click to see details on this item
1.1.1.181Name: cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase
Other names: 3beta-hydroxy-Delta5-C27-steroid oxidoreductase

click to see details on this item
[c] : nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




click to see details on this item + xol7aName: 7 alpha-Hydroxycholesterol
Formula: C27H46O2
Charge: 0




click to see details on this item
hName: H+
Formula: H
Charge: 1




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




click to see details on this item + xol7aoneName: 7alpha-Hydroxycholest-4-en-3-one
Formula: C27H44O2
Charge: 0




click to see details on this item
hsd-1 | hsd-2 | hsd-3
Biosynthesis of bile acid-like molecules
RC08723Name: 3beta-hydroxy-Delta5-C27-steroid oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R08723

click to see details on this item
1.1.1.181Name: cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase
Other names: 3beta-hydroxy-Delta5-C27-steroid oxidoreductase

click to see details on this item
[c] : xoltri25Name: "7-alpha,25-Dihydroxycholesterol"
Formula: C27H46O3
Charge: 0




click to see details on this item + nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




click to see details on this item
xol25oneName: 7alpha,25-Dihydroxy-4-cholesten-3-one
Formula: C27H44O3
Charge: 0




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




click to see details on this item + hName: H+
Formula: H
Charge: 1




click to see details on this item
hsd-1 | hsd-2 | hsd-3
Biosynthesis of bile acid-like molecules
RC08724Name: 3beta-hydroxy-Delta5-C27-steroid oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R08724

click to see details on this item
1.1.1.181Name: cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase
Other names: 3beta-hydroxy-Delta5-C27-steroid oxidoreductase

click to see details on this item
[c] : nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




click to see details on this item + xoltri27Name: "7-alpha,27-Dihydroxycholesterol"
Formula: C27H46O3
Charge: 0




click to see details on this item
hName: H+
Formula: H
Charge: 1




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




click to see details on this item + xol27oneName: 7alpha,26-Dihydroxy-4-cholesten-3-one
Formula: C27H44O3
Charge: 0




click to see details on this item
hsd-1 | hsd-2 | hsd-3
Biosynthesis of bile acid-like molecules
The information and tools provided in this website are to be used for academic purposes only. Potential users of the flux analysis tools (FBA button in the vertical menu) are asked to show proof of working at an academic institution during the creation of their accounts. These mathematical tools are powered by the commercial software Gurobi.