WormFlux: mechanistic analysis of C. elegans metabolism

(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	1.1.1.27
Name .....................................................	:	L-lactate dehydrogenase, etc.Lactic acid dehydrogenase, L(+)-nLDH, L-(+)-lactate dehydrogenase, L-lactic dehydrogenase, L-lactic acid dehydrogenase, Lactate dehydrogenase, Lactate dehydrogenase NAD+-dependent, Lactic dehydrogenase, NAD+-lactate dehydrogenase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K00016LDH ldh; L-lactate dehydrogenase [EC:1.1.1.27]
Genes .....................................................	:	ldh-1
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below.

External links

KEGG

BRENDA

Reactions

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC03104Name: 3-Mercaptolactate:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R03104 click to see details on this item	1.1.1.27Name: L-lactate dehydrogenase Other names: lactic acid dehydrogenase, L(+)-nLDH, L-(+)-lactate dehydrogenase, L-lactic dehydrogenase, L-lactic acid dehydrogenase, lactate dehydrogenase, lactate dehydrogenase NAD+-dependent, lactic dehydrogenase, NAD+-lactate dehydrogenase click to see details on this item	[c] : mercplacName: 3-Mercaptolactate Formula: C3H5O3S Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	hName: H+ Formula: H Charge: 1 click to see details on this item + mercppyrName: Mercaptopyruvate Formula: C3H3O3S Charge: -1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	ldh-1	Miscellaneous
RC00703Name: (S)-Lactate:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00703 click to see details on this item	1.1.1.27Name: L-lactate dehydrogenase Other names: lactic acid dehydrogenase, L(+)-nLDH, L-(+)-lactate dehydrogenase, L-lactic dehydrogenase, L-lactic acid dehydrogenase, lactate dehydrogenase, lactate dehydrogenase NAD+-dependent, lactic dehydrogenase, NAD+-lactate dehydrogenase click to see details on this item	[c] : lac-LName: L-Lactate Formula: C3H5O3 Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	ldh-1	Glycolysis / gluconeogenesis
RC01000Name: 2-Hydroxybutyrate:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01000 click to see details on this item	1.1.1.27Name: L-lactate dehydrogenase Other names: lactic acid dehydrogenase, L(+)-nLDH, L-(+)-lactate dehydrogenase, L-lactic dehydrogenase, L-lactic acid dehydrogenase, lactate dehydrogenase, lactate dehydrogenase NAD+-dependent, lactic dehydrogenase, NAD+-lactate dehydrogenase click to see details on this item	[c] : 2hbName: 2-Hydroxybutyrate Formula: C4H7O3 Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	2obutName: 2-Oxobutanoate Formula: C4H5O3 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	ldh-1	Propionate degradation

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