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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.14.13.100
Name ..................................................... : 25/26-hydroxycholesterol 7alpha-hydroxylase, etc.25-hydroxycholesterol 7alpha-monooxygenase, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase, 27-hydroxycholesterol 7-monooxygenase, 27-hydroxycholesterol 7alpha-hydroxylase, Cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating), 25-hydroxycholesterol 7alpha-hydroxylase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : Not determined
Genes ..................................................... : Not determined
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC07209Name: oxysterol 7alpha-hydroxylase (acting on 25-hydroxycholesterol)
Type: Regular
Location: Cytosol
KEGG ID: R07209

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1.14.13.100Name: 25/26-hydroxycholesterol 7alpha-hydroxylase
Other names: 25-hydroxycholesterol 7alpha-monooxygenase, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase, 27-hydroxycholesterol 7-monooxygenase, 27-hydroxycholesterol 7alpha-hydroxylase, cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating), 25-hydroxycholesterol 7alpha-hydroxylase

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[c] : hName: H+
Formula: H
Charge: 1




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + xol25ohName: 25-Hydroxycholesterol
Formula: C27H46O2
Charge: 0




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h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + xoltri25Name: "7-alpha,25-Dihydroxycholesterol"
Formula: C27H46O3
Charge: 0




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To be determined
Biosynthesis of bile acid-like molecules
RC07372Name: oxysterol 7alpha-hydroxylase (acting on 27-hydroxycholesterol)
Type: Regular
Location: Cytosol
KEGG ID: R07372

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1.14.13.100Name: 25/26-hydroxycholesterol 7alpha-hydroxylase
Other names: 25-hydroxycholesterol 7alpha-monooxygenase, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase, 27-hydroxycholesterol 7-monooxygenase, 27-hydroxycholesterol 7alpha-hydroxylase, cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating), 25-hydroxycholesterol 7alpha-hydroxylase

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1.14.13.17Name: cholesterol 7alpha-monooxygenase
Other names: cholesterol 7alpha-hydroxylase, CYP7A1

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[c] : hName: H+
Formula: H
Charge: 1




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + xol27ohName: 27-Hydroxycholesterol
Formula: C27H46O2
Charge: 0




click to see details on this item
h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + xoltri27Name: "7-alpha,27-Dihydroxycholesterol"
Formula: C27H46O3
Charge: 0




click to see details on this item
To be determined
Biosynthesis of bile acid-like molecules
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