WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	2.4.2.7
Name .....................................................	:	Adenine phosphoribosyltransferase, etc.AMP pyrophosphorylase, Transphosphoribosidase, APRT, AMP-pyrophosphate phosphoribosyltransferase, Adenine phosphoribosylpyrophosphate transferase, Adenosine phosphoribosyltransferase, Adenylate pyrophosphorylase, Adenylic pyrophosphorylase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K00759APRT apt; adenine phosphoribosyltransferase [EC:2.4.2.7]
Genes .....................................................	:	T19B4.3
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below.

External links

KEGG

BRENDA

Reactions

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00190Name: AMP:diphosphate phospho-D-ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R00190 click to see details on this item	2.4.2.7Name: adenine phosphoribosyltransferase Other names: AMP pyrophosphorylase, transphosphoribosidase, APRT, AMP-pyrophosphate phosphoribosyltransferase, adenine phosphoribosylpyrophosphate transferase, adenosine phosphoribosyltransferase, adenylate pyrophosphorylase, adenylic pyrophosphorylase click to see details on this item 2.4.2.8Name: hypoxanthine phosphoribosyltransferase Other names: IMP pyrophosphorylase, transphosphoribosidase, hypoxanthine---guanine phosphoribosyltransferase, guanine phosphoribosyltransferase, GPRT, HPRT, guanosine 5'-phosphate pyrophosphorylase, IMP-GMP pyrophosphorylase, HGPRTase, 6-hydroxypurine phosphoribosyltransferase, 6-mercaptopurine phosphoribosyltransferase, GMP pyrophosphorylase, guanine-hypoxanthine phosphoribosyltransferase, guanosine phosphoribosyltransferase, guanylate pyrophosphorylase, guanylic pyrophosphorylase, inosinate pyrophosphorylase, inosine 5'-phosphate pyrophosphorylase, inosinic acid pyrophosphorylase, inosinic pyrophosphorylase, 6-mercaptopurine phosphoribosyltransferase, purine-6-thiol phosphoribosyltransferase click to see details on this item	[c] : adeName: Adenine Formula: C5H5N5 Charge: 0 click to see details on this item + prppName: 5-Phospho-alpha-D-ribose 1-diphosphate Formula: C5H8O14P3 Charge: -5 click to see details on this item		ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	T19B4.3 \| hprt-1	Purine metabolism
RC01229Name: GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R01229 click to see details on this item	2.4.2.7Name: adenine phosphoribosyltransferase Other names: AMP pyrophosphorylase, transphosphoribosidase, APRT, AMP-pyrophosphate phosphoribosyltransferase, adenine phosphoribosylpyrophosphate transferase, adenosine phosphoribosyltransferase, adenylate pyrophosphorylase, adenylic pyrophosphorylase click to see details on this item 2.4.2.8Name: hypoxanthine phosphoribosyltransferase Other names: IMP pyrophosphorylase, transphosphoribosidase, hypoxanthine---guanine phosphoribosyltransferase, guanine phosphoribosyltransferase, GPRT, HPRT, guanosine 5'-phosphate pyrophosphorylase, IMP-GMP pyrophosphorylase, HGPRTase, 6-hydroxypurine phosphoribosyltransferase, 6-mercaptopurine phosphoribosyltransferase, GMP pyrophosphorylase, guanine-hypoxanthine phosphoribosyltransferase, guanosine phosphoribosyltransferase, guanylate pyrophosphorylase, guanylic pyrophosphorylase, inosinate pyrophosphorylase, inosine 5'-phosphate pyrophosphorylase, inosinic acid pyrophosphorylase, inosinic pyrophosphorylase, 6-mercaptopurine phosphoribosyltransferase, purine-6-thiol phosphoribosyltransferase click to see details on this item	[c] : guaName: Guanine Formula: C5H5N5O Charge: 0 click to see details on this item + prppName: 5-Phospho-alpha-D-ribose 1-diphosphate Formula: C5H8O14P3 Charge: -5 click to see details on this item		gmpName: GMP Formula: C10H12N5O8P Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	T19B4.3 \| hprt-1	Purine metabolism

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