WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	4.1.1.15
Name .....................................................	:	Glutamate decarboxylase, etc.L-glutamic acid decarboxylase, L-glutamic decarboxylase, Cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, Aspartate 1-decarboxylase, Aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, Gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K01580E4.1.1.15 gadB gadA GAD; glutamate decarboxylase [EC:4.1.1.15]
Genes .....................................................	:	unc-25
Localization .....................................................	:	Cytosol, Mitochondria
Other associations .....................................................	:	See reaction table below (6 reactions in total)

External links

KEGG

BRENDA

Reactions

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00261Name: L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming) Type: Regular Location: Cytosol KEGG ID: R00261 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[c] : glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	4abutName: 4-Aminobutanoate Formula: C4H9NO2 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	unc-25	Glutamate / glutamine metabolism
RM00261Name: L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming) Type: Regular Location: Mitochondria KEGG ID: R00261 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[m] : glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	4abutName: 4-Aminobutanoate Formula: C4H9NO2 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	unc-25	Glutamate / glutamine metabolism
RC00489Name: L-aspartate 1-carboxy-lyase (beta-alanine-forming) Type: Regular Location: Cytosol KEGG ID: R00489 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[c] : asp-LName: L-Aspartate Formula: C4H6NO4 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	unc-25	Aspartate and asparagine metabolism
RM00489Name: L-aspartate 1-carboxy-lyase (beta-alanine-forming) Type: Regular Location: Mitochondria KEGG ID: R00489 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[m] : asp-LName: L-Aspartate Formula: C4H6NO4 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	unc-25	Aspartate and asparagine metabolism
RC01682Name: 3-Sulfo-L-alanine carboxy-lyase (taurine-forming) Type: Regular Location: Cytosol KEGG ID: R01682 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[c] : LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + taurName: Taurine Formula: C2H7NO3S Charge: 0 click to see details on this item	unc-25	Taurine and hypotaurine metabolism
RC02466Name: 3-Sulfino-L-alanine carboxy-lyase Type: Regular Location: Cytosol KEGG ID: R02466 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[c] : 3salaName: 3-Sulfino-L-alanine Formula: C3H5NO4S Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + hyptaurName: Hypotaurine Formula: C2H6NO2S Charge: -1 click to see details on this item	unc-25	Taurine and hypotaurine metabolism

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