HOME DOWNLOAD CITATION HELP
Umass Logo PSB Logo
(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 6.1.1.4
Name ..................................................... : Leucine---tRNA ligase, etc.Leucyl-tRNA synthetase, Leucyl-transfer ribonucleate synthetase, Leucyl-transfer RNA synthetase, Leucyl-transfer ribonucleic acid synthetase, Leucine-tRNA synthetase, Leucine translase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K01869LARS leuS; leucyl-tRNA synthetase [EC:6.1.1.4]
Genes ..................................................... : lars-1, lars-2
Localization ..................................................... : Cytosol, Mitochondria
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC03657Name: L-Leucine:tRNA(Leu) ligase (AMP-forming)
Type: Regular
Location: Cytosol
KEGG ID: R03657

click to see details on this item
6.1.1.4Name: leucine---tRNA ligase
Other names: leucyl-tRNA synthetase, leucyl-transfer ribonucleate synthetase, leucyl-transfer RNA synthetase, leucyl-transfer ribonucleic acid synthetase, leucine-tRNA synthetase, leucine translase

click to see details on this item
[c] : atpName: ATP
Formula: C10H12N5O13P3
Charge: -4




click to see details on this item + leu-LName: L-Leucine
Formula: C6H13NO2
Charge: 0




click to see details on this item + trnaleuName: tRNA(Leu)
Formula: ROH
Charge: 0




click to see details on this item
ampName: AMP
Formula: C10H12N5O7P
Charge: -2




click to see details on this item + leutrnaName: L-Leucyl-tRNA(Leu)
Formula: C6H13NO2R
Charge: 1




click to see details on this item + ppiName: Diphosphate
Formula: HO7P2
Charge: -3




click to see details on this item
lars-1
Aminoacyl-tRNA biosynthesis
RM03657Name: L-Leucine:tRNA(Leu) ligase (AMP-forming)
Type: Regular
Location: Mitochondria
KEGG ID: R03657

click to see details on this item
6.1.1.4Name: leucine---tRNA ligase
Other names: leucyl-tRNA synthetase, leucyl-transfer ribonucleate synthetase, leucyl-transfer RNA synthetase, leucyl-transfer ribonucleic acid synthetase, leucine-tRNA synthetase, leucine translase

click to see details on this item
[m] : atpName: ATP
Formula: C10H12N5O13P3
Charge: -4




click to see details on this item + leu-LName: L-Leucine
Formula: C6H13NO2
Charge: 0




click to see details on this item + trnaleuName: tRNA(Leu)
Formula: ROH
Charge: 0




click to see details on this item
ampName: AMP
Formula: C10H12N5O7P
Charge: -2




click to see details on this item + leutrnaName: L-Leucyl-tRNA(Leu)
Formula: C6H13NO2R
Charge: 1




click to see details on this item + ppiName: Diphosphate
Formula: HO7P2
Charge: -3




click to see details on this item
lars-2
Aminoacyl-tRNA biosynthesis
The information and tools provided in this website are to be used for academic purposes only. Potential users of the flux analysis tools (FBA button in the vertical menu) are asked to show proof of working at an academic institution during the creation of their accounts. These mathematical tools are powered by the commercial software Gurobi.