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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 6.3.4.3
Name ..................................................... : Formate---tetrahydrofolate ligase, etc.Formyltetrahydrofolate synthetase, 10-formyltetrahydrofolate synthetase, Tetrahydrofolic formylase, Tetrahydrofolate formylase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00288MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Genes ..................................................... : K07E3.4
Localization ..................................................... : Cytosol, Mitochondria
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC00943Name: Formate:tetrahydrofolate ligase (ADP-forming)
Type: Regular
Location: Cytosol
KEGG ID: R00943

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6.3.4.3Name: formate---tetrahydrofolate ligase
Other names: formyltetrahydrofolate synthetase, 10-formyltetrahydrofolate synthetase, tetrahydrofolic formylase, tetrahydrofolate formylase

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[c] : atpName: ATP
Formula: C10H12N5O13P3
Charge: -4




click to see details on this item + forName: Formate
Formula: CH1O2
Charge: -1




click to see details on this item + thfName: "5,6,7,8-Tetrahydrofolate"
Formula: C19H21N7O6
Charge: -2




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10fthfName: 10-Formyltetrahydrofolate
Formula: C20H21N7O7
Charge: -2




click to see details on this item + adpName: ADP
Formula: C10H12N5O10P2
Charge: -3




click to see details on this item + piName: Phosphate
Formula: HO4P
Charge: -2




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K07E3.4
Folate cycle
RM00943Name: Formate:tetrahydrofolate ligase (ADP-forming)
Type: Regular
Location: Mitochondria
KEGG ID: R00943

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6.3.4.3Name: formate---tetrahydrofolate ligase
Other names: formyltetrahydrofolate synthetase, 10-formyltetrahydrofolate synthetase, tetrahydrofolic formylase, tetrahydrofolate formylase

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[m] : atpName: ATP
Formula: C10H12N5O13P3
Charge: -4




click to see details on this item + forName: Formate
Formula: CH1O2
Charge: -1




click to see details on this item + thfName: "5,6,7,8-Tetrahydrofolate"
Formula: C19H21N7O6
Charge: -2




click to see details on this item
10fthfName: 10-Formyltetrahydrofolate
Formula: C20H21N7O7
Charge: -2




click to see details on this item + adpName: ADP
Formula: C10H12N5O10P2
Charge: -3




click to see details on this item + piName: Phosphate
Formula: HO4P
Charge: -2




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K07E3.4
Folate cycle
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