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  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Reaction Overview
Model ID ..................................................... : RCC0200
Name ..................................................... : Ascarylose synthesis
Type (?)

One of the following categories:

Regular: Regular enzymatic reactions that do not fit in any special categories below
Biomass: Reactions that represent the assembly of the worm biomass
Degradation: Reactions that represent the degradation of the bacterial diet
Demand: Reactions that consume products in the compartment that they are produced
Sink: Reactions that can not only consume but also provide a metabolite in a particular compartment (e.g., storage reactions)
Transport: Reactions that transport material between different compartments
Exchange: Reactions that exchange metabolites with the environment
..................................................... 		: Regular
KEGG ID (?) Reactions in KEGG database that match this reaction.

Multiple IDs typically indicate that the model reaction is a merged reaction. ..................................................... 		: R00956, R02426, R03392, R08708, R08709
Is in PRIME model (?) Indicates whether the reaction is part of the PRIME model, which is the basis (minimum model) for proper biomass/energy generation and compartmentalization. ..................................................... : No
Reversibility ..................................................... : Irreversible
Localization ..................................................... : Cytosol
Other annotation ..................................................... : See tabular representation below.
Comments
  • Merged pathway based on that in Yesina.app. The biosynthesis of ascarylose in C. elegans is yet unknown.
  • See also note #37.

    • ► | Localization scores (click to view)▼ | Localization scores (click to hide)
    Not available
    ► | Reversibility scores (click to view)▼ | Reversibility scores (click to hide)

    Score tables (?) Reaction directionality scores for the KEGG reaction(s) that are associated with this model reaction. Different sources are used and evidence is culminated for each direction with respect to the KEGG reaction (click reaction IDs to reach relevant KEGG pages).

    R00956
    Source Forward Backward Reversible
    MetaCyc (?) Score of 1 represents the direction of the reaction as indicated in MetaCyc. 0 0 1
    SEED (?) Score of 1 represents the direction of the reaction as indicated in the SEED database. 0 0 1
    BiGG (?) Score represents 0.5 times the number of models with the indicated direction for this reaction in the BiGG database. Not available Not available Not available
    BRENDA (?) Score represents the proportion of reactions with the indicated direction reported in the BRENDA database for the enzymes associated with this reaction. Only reactions with a reported direction were used in the calculation. 0.00 0.00 1.00
    Total (?) If no direction has >0.5 points, reaction is considered reversible. If the score of one direction with the highest score is more than 25% larger than the next highest score, the direction with the highest score is taken. Else, reaction is considered reversible. Exceptions (i.e., cases when these rules are overridden by other criteria) are idicated in general comments to the reaction. 0.00 0.00 3.00
    Reaction
    ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

    I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
    & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

    If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.     		Pathway
    RCC0200Name: Ascarylose synthesis
    Type: Regular
    Location: Cytosol
    KEGG ID: R00956;R02426;R03392;R08708;R08709

    click to see details on this item
    2.7.7.33Name: glucose-1-phosphate cytidylyltransferase
    Other names: CDP glucose pyrophosphorylase, cytidine diphosphoglucose pyrophosphorylase, cytidine diphosphate glucose pyrophosphorylase, cytidine diphosphate-D-glucose pyrophosphorylase, CTP:D-glucose-1-phosphate cytidylyltransferase

    click to see details on this item
    4.2.1.45Name: CDP-glucose 4,6-dehydratase
    Other names: cytidine diphosphoglucose oxidoreductase, CDP-glucose 4,6-hydro-lyase

    click to see details on this item
    1.17.1.1Name: CDP-4-dehydro-6-deoxyglucose reductase
    Other names: CDP-4-keto-6-deoxyglucose reductase, cytidine diphospho-4-keto-6-deoxy-D-glucose reductase, cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase, CDP-4-keto-deoxy-glucose reductase, CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system, NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase

    click to see details on this item
    5.1.3.-Name: ascarylose synthesis

    click to see details on this item
    1.1.1.-Name: ascarylose synthesis

    click to see details on this item
    [c] : g1pName: D-Glucose 1-phosphate
    Formula: C6H11O9P
    Charge: -2




    click to see details on this item     + nadhName: Nicotinamide adenine dinucleotide - reduced
    Formula: C21H27N7O14P2
    Charge: -2




    click to see details on this item     + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
    Formula: C21H26N7O17P3
    Charge: -4




    click to see details on this item     + ctpName: CTP
    Formula: C9H12N3O14P3
    Charge: -4




    click to see details on this item     + (2) hName: H+
    Formula: H
    Charge: 1




    click to see details on this item
    cdpasclName: CDP-ascarylose
    Formula: C15H23N3O14P2
    Charge: -2




    click to see details on this item     + h2oName: H2O
    Formula: H2O
    Charge: 0




    click to see details on this item     + (2) piName: Phosphate
    Formula: HO4P
    Charge: -2




    click to see details on this item     + nadName: Nicotinamide adenine dinucleotide
    Formula: C21H26N7O14P2
    Charge: -1




    click to see details on this item     + nadpName: Nicotinamide adenine dinucleotide phosphate
    Formula: C21H25N7O17P3
    Charge: -3




    click to see details on this item
    Unknown
    Ascaroside biosynthesis
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