Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	etfox
Name .....................................................	:	Electron transfer flavoprotein oxidized, etc.Electron-transferring flavoprotein, Electron-transfer flavoprotein
Model ID .....................................................	:	C04253
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C04253
Formula .....................................................	:	R
Charge .....................................................	:	0
Localization .....................................................	:	Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	etfox
Other associations .....................................................	:	See reaction table below (14 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Represented in 6 maps... Isoleucine degradation Leucine degradation Lysine degradation Mitochondrial fatty acid degradation Propionate degradation Valine degradation   Go to map

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM01282Name: Palmitoyl-CoA:oxygen 2-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R01282 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item 1.3.8.9Name: very-long-chain acyl-CoA dehydrogenase Other names: ACADVL (gene name). click to see details on this item	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + pmtcoaName: Palmitoyl-CoA (n-C16:0CoA) Formula: C37H62N7O17P3S Charge: -4 click to see details on this item		etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item + hdd2coaName: trans-Hexadec-2-enoyl-CoA Formula: C37H60N7O17P3S Charge: -4 click to see details on this item	(acdh-7 | acdh-8 | acdh-10) | acdh-12	Mitochondrial fatty acid degradation
RM03990Name: Tetradecanoyl-CoA:(acceptor) 2,3-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03990 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item 1.3.8.9Name: very-long-chain acyl-CoA dehydrogenase Other names: ACADVL (gene name). click to see details on this item	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + tdcoaName: Tetradecanoyl-CoA (n-C14:0CoA) Formula: C35H58N7O17P3S Charge: -4 click to see details on this item		etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item + td2coaName: trans-Tetradec-2-enoyl-CoA Formula: C35H56N7O17P3S Charge: -4 click to see details on this item	(acdh-7 | acdh-8 | acdh-10) | acdh-12	Mitochondrial fatty acid degradation
RM03857Name: Lauroyl-CoA:(acceptor) 2,3-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03857 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item	[m] : ddcacoaName: Dodecanoyl-CoA (n-C12:0CoA) Formula: C33H54N7O17P3S Charge: -4 click to see details on this item + etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item		dd2coaName: trans-Dodec-2-enoyl-CoA Formula: C33H52N7O17P3S Charge: -4 click to see details on this item + etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item	(acdh-7 | acdh-8 | acdh-10)	Mitochondrial fatty acid degradation
RM04754Name: Decanoyl-CoA:(acceptor) 2,3-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04754 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item	[m] : dcacoaName: Decanoyl-CoA (n-C10:0CoA) Formula: C31H50N7O17P3S Charge: -4 click to see details on this item + etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item		dc2coaName: trans-Dec-2-enoyl-CoA Formula: C31H48N7O17P3S Charge: -4 click to see details on this item + etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item	(acdh-7 | acdh-8 | acdh-10)	Mitochondrial fatty acid degradation
RM03777Name: Octanoyl-CoA:oxygen 2-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03777 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item 1.3.8.1Name: short-chain acyl-CoA dehydrogenase Other names: butyryl-CoA dehydrogenase, butanoyl-CoA dehydrogenase, butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, 3-hydroxyacyl CoA reductase, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, ACADS (gene name). click to see details on this item	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + occoaName: Octanoyl-CoA (n-C8:0CoA) Formula: C29H46N7O17P3S Charge: -4 click to see details on this item		etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item + oc2coaName: trans-Oct-2-enoyl-CoA Formula: C29H44N7O17P3S Charge: -4 click to see details on this item	(acdh-7 | acdh-8 | acdh-10) | (acdh-1 | acdh-2)	Mitochondrial fatty acid degradation
RM04751Name: Hexanoyl-CoA:(acceptor) 2,3-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04751 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item 1.3.8.1Name: short-chain acyl-CoA dehydrogenase Other names: butyryl-CoA dehydrogenase, butanoyl-CoA dehydrogenase, butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, 3-hydroxyacyl CoA reductase, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, ACADS (gene name). click to see details on this item	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + hxcoaName: Hexanoyl-CoA (n-C6:0CoA) Formula: C27H42N7O17P3S Charge: -4 click to see details on this item		etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item + hx2coaName: trans-Hex-2-enoyl-CoA Formula: C27H40N7O17P3S Charge: -4 click to see details on this item	(acdh-7 | acdh-8 | acdh-10) | (acdh-1 | acdh-2)	Mitochondrial fatty acid degradation
RM01175Name: Butanoyl-CoA:oxygen 2-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R01175 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item 1.3.8.1Name: short-chain acyl-CoA dehydrogenase Other names: butyryl-CoA dehydrogenase, butanoyl-CoA dehydrogenase, butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, 3-hydroxyacyl CoA reductase, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, ACADS (gene name). click to see details on this item	[m] : btcoaName: Butanoyl-CoA Formula: C25H38N7O17P3S Charge: -4 click to see details on this item + etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item		b2coaName: Crotonoyl-CoA Formula: C25H36N7O17P3S Charge: -4 click to see details on this item + etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item	(acdh-7 | acdh-8 | acdh-10) | (acdh-1 | acdh-2)	Mitochondrial fatty acid degradation
RM02488Name: Glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating) Type: Regular Location: Mitochondria KEGG ID: R02488 click to see details on this item	1.3.8.6Name: glutaryl-CoA dehydrogenase (ETF) Other names: glutaryl coenzyme A dehydrogenase, glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating), glutaryl-CoA dehydrogenase click to see details on this item	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + glutcoaName: Glutaryl-CoA Formula: C26H37N7O19P3S Charge: -5 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		b2coaName: Crotonoyl-CoA Formula: C25H36N7O17P3S Charge: -4 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item	F54D5.7	Lysine degradation
RMC0155Name: electron transfer flavoprotein Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	Not applicable	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + fadh2Name: Flavin adenine dinucleotide reduced Formula: C27H33N9O15P2 Charge: -2 click to see details on this item		etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item + fadName: Flavin adenine dinucleotide oxidized Formula: C27H31N9O15P2 Charge: -2 click to see details on this item	Not applicable	Miscellaneous
RM04433Name: Electron-transferring-flavoprotein:ubiquinone oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04433 click to see details on this item	1.5.5.1Name: electron-transferring-flavoprotein dehydrogenase Other names: ETF-QO, ETF:ubiquinone oxidoreductase, electron transfer flavoprotein dehydrogenase, electron transfer flavoprotein Q oxidoreductase, electron transfer flavoprotein-ubiquinone oxidoreductase, electron transfer flavoprotein reductase click to see details on this item	[m] : etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item + qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item		etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item	let-721 & (F27D4.1 & F23C8.5)	Miscellaneous
RM04432Name: Propanoyl-CoA:(acceptor) 2,3-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04432 click to see details on this item	1.3.8.1Name: short-chain acyl-CoA dehydrogenase Other names: butyryl-CoA dehydrogenase, butanoyl-CoA dehydrogenase, butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, 3-hydroxyacyl CoA reductase, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, ACADS (gene name). click to see details on this item	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + ppcoaName: Propanoyl-CoA Formula: C24H36N7O17P3S Charge: -4 click to see details on this item		etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item + prpncoaName: Propenoyl-CoA Formula: C24H34N7O17P3S Charge: -4 click to see details on this item	acdh-1	Propionate degradation
RM04096Name: 3-Methylbutanoyl-CoA:(acceptor) 2,3-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04095 click to see details on this item	1.3.8.4Name: isovaleryl-CoA dehydrogenase Other names: isovaleryl-coenzyme A dehydrogenase, isovaleroyl-coenzyme A dehydrogenase, 3-methylbutanoyl-CoA:(acceptor) oxidoreductase click to see details on this item	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + ivcoaName: Isovaleryl-CoA Formula: C26H40N7O17P3S Charge: -4 click to see details on this item		3mb2coaName: 3-Methylbut-2-enoyl-CoA Formula: C26H38N7O17P3S Charge: -4 click to see details on this item + etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item	ivd-1	Leucine degradation
RM02661Name: 2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R02661 click to see details on this item	1.3.99.12Name: 2-methylacyl-CoA dehydrogenase Other names: branched-chain acyl-CoA dehydrogenase, 2-methyl branched chain acyl-CoA dehydrogenase, 2-methylbutanoyl-CoA:(acceptor) oxidoreductase click to see details on this item 1.3.99.3Name: 2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase click to see details on this item	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + ibcoaName: Isobutyryl-CoA Formula: C25H38N7O17P3S Charge: -4 click to see details on this item		2mp2coaName: 2-Methylprop-2-enoyl-CoA Formula: C25H36N7O17P3S Charge: -4 click to see details on this item + etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item	(acdh-1 | acdh-2 | acdh-3) | acdh-9	Valine degradation
RM03172Name: (S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03172 click to see details on this item	1.3.99.12Name: 2-methylacyl-CoA dehydrogenase Other names: branched-chain acyl-CoA dehydrogenase, 2-methyl branched chain acyl-CoA dehydrogenase, 2-methylbutanoyl-CoA:(acceptor) oxidoreductase click to see details on this item 1.3.8.1Name: short-chain acyl-CoA dehydrogenase Other names: butyryl-CoA dehydrogenase, butanoyl-CoA dehydrogenase, butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, 3-hydroxyacyl CoA reductase, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, ACADS (gene name). click to see details on this item	[m] : 2mbcoaName: 2-Methylbutanoyl-CoA Formula: C26H40N7O17P3S Charge: -4 click to see details on this item + etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item		2mb2coaName: trans-2-Methylbut-2-enoyl-CoA Formula: C26H38N7O17P3S Charge: -4 click to see details on this item + etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item	acdh-1 | acdh-2 | acdh-3	Isoleucine degradation

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