Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	q
Name .....................................................	:	Ubiquinone, etc.Coenzyme Q, CoQ, Q
Model ID .....................................................	:	C00399
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00399
Formula .....................................................	:	C14H18O4
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	q
Other associations .....................................................	:	See reaction table below (14 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Represented in 7 maps... Electron transport chain (m) Glycerophospholipid metabolism (m) Pyrimidine metabolism (m) Reactive oxygen species metabolism (c) Sulfur metabolism (m) TCA cycle (m) Ubiquinone metabolism (m)   Go to map

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM02164Name: Succinate:ubiquinone oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R02164 click to see details on this item	1.3.5.1Name: succinate dehydrogenase (quinone) Other names: succinate dehydrogenase (ubiquinone), succinic dehydrogenase, complex II (ambiguous), succinate dehydrogenase complex, SDH, succinate:ubiquinone oxidoreductase click to see details on this item	[m] : qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item		qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item + fumName: Fumarate Formula: C4H2O4 Charge: -2 click to see details on this item	[(sdha-1 | sdha-2) & sdhb-1] & mev-1 & sdhd-1	Electron transport chain
RM08657Name: sn-glycerol 3-phosphate:quinone oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: R08657 click to see details on this item	1.1.5.3Name: glycerol-3-phosphate dehydrogenase Other names: alpha-glycerophosphate dehydrogenase, alpha-glycerophosphate dehydrogenase (acceptor), anaerobic glycerol-3-phosphate dehydrogenase, DL-glycerol 3-phosphate oxidase (misleading), FAD-dependent glycerol-3-phosphate dehydrogenase, FAD-dependent sn-glycerol-3-phosphate dehydrogenase, FAD-GPDH, FAD-linked glycerol 3-phosphate dehydrogenase, FAD-linked L-glycerol-3-phosphate dehydrogenase, flavin-linked glycerol-3-phosphate dehydrogenase, flavoprotein-linked L-glycerol 3-phosphate dehydrogenase, glycerol 3-phosphate cytochrome c reductase (misleading), glycerol phosphate dehydrogenase, glycerol phosphate dehydrogenase (acceptor), glycerol phosphate dehydrogenase (FAD), glycerol-3-phosphate CoQ reductase, glycerol-3-phosphate dehydrogenase (flavin-linked), glycerol-3-phosphate:CoQ reductase, glycerophosphate dehydrogenase, L-3-glycerophosphate-ubiquinone oxidoreductase, L-glycerol-3-phosphate dehydrogenase (ambiguous), L-glycerophosphate dehydrogenase, mGPD, mitochondrial glycerol phosphate dehydrogenase, NAD+-independent glycerol phosphate dehydrogenase, pyridine nucleotide-independent L-glycerol 3-phosphate dehydrogenase, sn-glycerol 3-phosphate oxidase (misleading), sn-glycerol-3-phosphate dehydrogenase, sn-glycerol-3-phosphate:(acceptor) 2-oxidoreductase, sn-glycerol-3-phosphate:acceptor 2-oxidoreductase click to see details on this item	qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item[m] + glyc3pName: Glycerol 3-phosphate Formula: C3H7O6P Charge: -2 click to see details on this item[c]		dhapName: Dihydroxyacetone phosphate Formula: C3H5O6P Charge: -2 click to see details on this item[c] + qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item[m]	T25G3.4 | Y50E8A.6	Glycerophospholipid metabolism
RC02364Name: NADPH2:quinone oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02364 click to see details on this item	1.6.5.5Name: NADPH:quinone reductase Other names: NADPH2:quinone reductase click to see details on this item	[c] : hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item		nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item	F39B2.3	Reactive oxygen species metabolism
RMC0027Name: artificial quinone conversion (q8 to q pool) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	Not applicable	[m] : q8Name: Ubiquinone-8 Formula: C49H74O4 Charge: 0 click to see details on this item		qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item	Not applicable	Ubiquinone metabolism
RMC0028Name: artificial quinone conversion (q9 to q pool) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	Not applicable	[m] : q9Name: Ubiquinone-9 Formula: C54H82O4 Charge: 0 click to see details on this item		qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item	Not applicable	Ubiquinone metabolism
RM04433Name: Electron-transferring-flavoprotein:ubiquinone oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04433 click to see details on this item	1.5.5.1Name: electron-transferring-flavoprotein dehydrogenase Other names: ETF-QO, ETF:ubiquinone oxidoreductase, electron transfer flavoprotein dehydrogenase, electron transfer flavoprotein Q oxidoreductase, electron transfer flavoprotein-ubiquinone oxidoreductase, electron transfer flavoprotein reductase click to see details on this item	[m] : etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item + qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item		etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item	let-721 & (F27D4.1 & F23C8.5)	Miscellaneous
RMC0006Name: NADH:ubiquinone oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: R02163 click to see details on this item	1.6.5.3Name: NADH:ubiquinone reductase (H+-translocating) Other names: ubiquinone reductase, type 1 dehydrogenase, complex 1 dehydrogenase, coenzyme Q reductase, complex I (electron transport chain), complex I (mitochondrial electron transport), complex I (NADH:Q1 oxidoreductase), dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, mitochondrial electron transport complex 1, mitochondrial electron transport complex I, NADH coenzyme Q1 reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase, NADH-ubiquinone reductase, NADH-ubiquinone oxidoreductase, NADH-ubiquinone-1 reductase, reduced nicotinamide adenine dinucleotide-coenzyme Q reductase, NADH:ubiquinone oxidoreductase complex, NADH-Q6 oxidoreductase, electron transfer complex I, NADH2 dehydrogenase (ubiquinone) click to see details on this item 1.6.99.3Name: NADH dehydrogenase Other names: cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase, dihydrocodehydrogenase I dehydrogenase, dihydronicotinamide adenine dinucleotide dehydrogenase, diphosphopyridine diaphorase, DPNH diaphorase, NADH diaphorase, NADH hydrogenase, NADH oxidoreductase, NADH-menadione oxidoreductase, reduced diphosphopyridine nucleotide diaphorase, NADH:cytochrome c oxidoreductase, NADH2 dehydrogenase, NADH:(acceptor) oxidoreductase click to see details on this item	qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item[m] + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item[m] + (5.0) hName: H+ Formula: H Charge: 1 click to see details on this item[m]		qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item[m] + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item[m] + (4.0) hName: H+ Formula: H Charge: 1 click to see details on this item[c]	(nduo-1 & nduo-2 & nduo-3 & nduo-4 & nduo-5 & nduo-6 & ndfl-4) & [F53F4.10 & (gas-1 | nduf-2.2) & nuo-2 & nuo-1 & nuo-5 & nduf-7 & T20H4.5 & lpd-5 & nduf-5 & nduf-6] & [F31D4.9 & Y63D3A.7 & C33A12.1 & nuo-3 & F45H10.3 & Y54F10AM.5 & Y53G8AL.2 & nuo-4 & (F37C12.3 | Y56A3A.19) & C34B2.8] & (F44G4.2 & C18E9.4 & nuo-6 & C25H3.9 & ZK809.3 & D2030.4 & Y51H1A.3 & C16A3.5 & F59C6.5 & Y71H2AM.4 & F42G8.10)	Electron transport chain
RM02161Name: Ubiquinol:ferricytochrome-c oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: R02161 click to see details on this item	1.10.2.2Name: quinol---cytochrome-c reductase Other names: ubiquinol---cytochrome-c reductase, coenzyme Q-cytochrome c reductase, dihydrocoenzyme Q-cytochrome c reductase, reduced ubiquinone-cytochrome c reductase, complex III (mitochondrial electron transport), ubiquinone-cytochrome c reductase, ubiquinol-cytochrome c oxidoreductase, reduced coenzyme Q-cytochrome c reductase, ubiquinone-cytochrome c oxidoreductase, reduced ubiquinone-cytochrome c oxidoreductase, mitochondrial electron transport complex III, ubiquinol-cytochrome c-2 oxidoreductase, ubiquinone-cytochrome b-c1 oxidoreductase, ubiquinol-cytochrome c2 reductase, ubiquinol-cytochrome c1 oxidoreductase, CoQH2-cytochrome c oxidoreductase, ubihydroquinol:cytochrome c oxidoreductase, coenzyme QH2-cytochrome c reductase, QH2:cytochrome c oxidoreductase, ubiquinol:ferricytochrome-c oxidoreductase click to see details on this item	(2.0) ficytCName: Ferricytochrome c Formula: C42H42FeN8O8S2R4 Charge: 1 click to see details on this item[m] + (2.0) hName: H+ Formula: H Charge: 1 click to see details on this item[m] + qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item[m]		(2.0) focytCName: Ferrocytochrome C Formula: C42H42FeN8O8S2R4 Charge: 0 click to see details on this item[m] + (4.0) hName: H+ Formula: H Charge: 1 click to see details on this item[c] + qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item[m]	isp-1 & ctb-1 & cyc-1 & (ucr-2.3 | ucr-2.1 | ucr-2.2) & T27E9.2 & T02H6.11 & (F45H10.2 | R07E4.3) & ucr-11 & (cyc-2.1 | cyc-2.2)	Electron transport chain
RMC0007Name: NADH:ubiquinone oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: R02163 click to see details on this item	1.6.5.3Name: NADH:ubiquinone reductase (H+-translocating) Other names: ubiquinone reductase, type 1 dehydrogenase, complex 1 dehydrogenase, coenzyme Q reductase, complex I (electron transport chain), complex I (mitochondrial electron transport), complex I (NADH:Q1 oxidoreductase), dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, mitochondrial electron transport complex 1, mitochondrial electron transport complex I, NADH coenzyme Q1 reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase, NADH-ubiquinone reductase, NADH-ubiquinone oxidoreductase, NADH-ubiquinone-1 reductase, reduced nicotinamide adenine dinucleotide-coenzyme Q reductase, NADH:ubiquinone oxidoreductase complex, NADH-Q6 oxidoreductase, electron transfer complex I, NADH2 dehydrogenase (ubiquinone) click to see details on this item 1.6.99.3Name: NADH dehydrogenase Other names: cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase, dihydrocodehydrogenase I dehydrogenase, dihydronicotinamide adenine dinucleotide dehydrogenase, diphosphopyridine diaphorase, DPNH diaphorase, NADH diaphorase, NADH hydrogenase, NADH oxidoreductase, NADH-menadione oxidoreductase, reduced diphosphopyridine nucleotide diaphorase, NADH:cytochrome c oxidoreductase, NADH2 dehydrogenase, NADH:(acceptor) oxidoreductase click to see details on this item	qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item[m] + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item[m] + hName: H+ Formula: H Charge: 1 click to see details on this item[c]		qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item[m] + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item[m]	(nduo-1 & nduo-2 & nduo-3 & nduo-4 & nduo-5 & nduo-6 & ndfl-4) & [F53F4.10 & (gas-1 | nduf-2.2) & nuo-2 & nuo-1 & nuo-5 & nduf-7 & T20H4.5 & lpd-5 & nduf-5 & nduf-6] & [F31D4.9 & Y63D3A.7 & C33A12.1 & nuo-3 & F45H10.3 & Y54F10AM.5 & Y53G8AL.2 & nuo-4 & (F37C12.3 | Y56A3A.19) & C34B2.8] & (F44G4.2 & C18E9.4 & nuo-6 & C25H3.9 & ZK809.3 & D2030.4 & Y51H1A.3 & C16A3.5 & F59C6.5 & Y71H2AM.4 & F42G8.10)	Electron transport chain
RMC0008Name: NADH:ubiquinone oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R02163 click to see details on this item	1.6.5.3Name: NADH:ubiquinone reductase (H+-translocating) Other names: ubiquinone reductase, type 1 dehydrogenase, complex 1 dehydrogenase, coenzyme Q reductase, complex I (electron transport chain), complex I (mitochondrial electron transport), complex I (NADH:Q1 oxidoreductase), dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, mitochondrial electron transport complex 1, mitochondrial electron transport complex I, NADH coenzyme Q1 reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase, NADH-ubiquinone reductase, NADH-ubiquinone oxidoreductase, NADH-ubiquinone-1 reductase, reduced nicotinamide adenine dinucleotide-coenzyme Q reductase, NADH:ubiquinone oxidoreductase complex, NADH-Q6 oxidoreductase, electron transfer complex I, NADH2 dehydrogenase (ubiquinone) click to see details on this item 1.6.99.3Name: NADH dehydrogenase Other names: cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase, dihydrocodehydrogenase I dehydrogenase, dihydronicotinamide adenine dinucleotide dehydrogenase, diphosphopyridine diaphorase, DPNH diaphorase, NADH diaphorase, NADH hydrogenase, NADH oxidoreductase, NADH-menadione oxidoreductase, reduced diphosphopyridine nucleotide diaphorase, NADH:cytochrome c oxidoreductase, NADH2 dehydrogenase, NADH:(acceptor) oxidoreductase click to see details on this item	[m] : qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	(nduo-1 & nduo-2 & nduo-3 & nduo-4 & nduo-5 & nduo-6 & ndfl-4) & [F53F4.10 & (gas-1 | nduf-2.2) & nuo-2 & nuo-1 & nuo-5 & nduf-7 & T20H4.5 & lpd-5 & nduf-5 & nduf-6] & [F31D4.9 & Y63D3A.7 & C33A12.1 & nuo-3 & F45H10.3 & Y54F10AM.5 & Y53G8AL.2 & nuo-4 & (F37C12.3 | Y56A3A.19) & C34B2.8] & (F44G4.2 & C18E9.4 & nuo-6 & C25H3.9 & ZK809.3 & D2030.4 & Y51H1A.3 & C16A3.5 & F59C6.5 & Y71H2AM.4 & F42G8.10)	Electron transport chain
RM01868Name: (S)-dihydroorotate:quinone oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: R01868 click to see details on this item	1.3.5.2Name: dihydroorotate dehydrogenase (quinone) Other names: dihydroorotate:ubiquinone oxidoreductase, (S)-dihydroorotate:(acceptor) oxidoreductase, (S)-dihydroorotate:acceptor oxidoreductase, DHOdehase (ambiguous), DHOD (ambiguous), DHODase (ambiguous), DHODH click to see details on this item	dhor-SName: (S)-Dihydroorotate Formula: C5H5N2O4 Charge: -1 click to see details on this item[c] + qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item[m]		orotName: Orotate Formula: C5H3N2O4 Charge: -1 click to see details on this item[c] + qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item[m]	dhod-1	Pyrimidine metabolism
RMC0077Name: Sulfide:quinone oxidoreductase Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	1.8.5.-Name: sulfide:quinone oxidoreductase click to see details on this item	[m] : h2sName: Hydrogen sulfide Formula: H2S Charge: 0 click to see details on this item + qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item		sName: Sulfur Formula: S Charge: 0 click to see details on this item + qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item	sqrd-1	Sulfur metabolism
DMN0033Name: oxidation of quinone Type: Demand Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	[c] : qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item		qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item	Not applicable	Demand reactions
DMN0039Name: ubiquinone demand Type: Demand Location: Mitochondria KEGG ID: NA click to see details on this item	Not applicable	qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item[m]			Not applicable	Demand reactions

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