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Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
Metabolite Overview
Abbreviation ..................................................... : 7thf
Name ..................................................... : heptaglutamyl folate (THF)
Model ID ..................................................... : CC0005
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : Not available
Formula ..................................................... : C49H57N13O24
Charge ..................................................... : -8
Localization ..................................................... : Cytosol, Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : 7thf
Other associations ..................................................... : See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Folate cycle (m)
Comments
ERROR
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RMC0024Name: Tetrahydrofolyl-[Glu](n):L-glutamate gamma-ligase (ADP-forming) (producing 7thf)
Type: Regular
Location: Mitochondria
KEGG ID: R04241;R00942

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6.3.2.17Name: tetrahydrofolate synthase
Other names: folylpolyglutamate synthase, folate polyglutamate synthetase, formyltetrahydropteroyldiglutamate synthetase, N10-formyltetrahydropteroyldiglutamate synthetase, folylpoly-gamma-glutamate synthase, folylpolyglutamyl synthetase, folylpoly(gamma-glutamate) synthase, folylpolyglutamate synthetase, folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase, FPGS, tetrahydrofolylpolyglutamate synthase, tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming), tetrahydropteroyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)

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[m] : (2) atpName: ATP
Formula: C10H12N5O13P3
Charge: -4




click to see details on this item + (2) glu-LName: L-Glutamate
Formula: C5H8NO4
Charge: -1




click to see details on this item + 5thfName: pentaglutamyl folate (THF)
Formula: C39H45N11O18
Charge: -6




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7thfName: heptaglutamyl folate (THF)
Formula: C49H57N13O24
Charge: -8




click to see details on this item + (2) adpName: ADP
Formula: C10H12N5O10P2
Charge: -3




click to see details on this item + (2) hName: H+
Formula: H
Charge: 1




click to see details on this item + (2) piName: Phosphate
Formula: HO4P
Charge: -2




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F25B5.6
Folate cycle
DMN0046Name: polyglutamylated thf demand (cytosol)
Type: Demand
Location: Cytosol
KEGG ID: NA

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Not applicable
7thfName: heptaglutamyl folate (THF)
Formula: C49H57N13O24
Charge: -8




click to see details on this item[c]
Not applicable
Demand reactions
DMN0047Name: polyglutamylated thf demand (mitochondrial)
Type: Demand
Location: Mitochondria
KEGG ID: NA

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Not applicable
7thfName: heptaglutamyl folate (THF)
Formula: C49H57N13O24
Charge: -8




click to see details on this item[m]
Not applicable
Demand reactions
TCM0174Name: heptaglutamyl folate (THF) transport
Type: Transport
Location: Cytosol, Mitochondria
KEGG ID: NA

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Not applicable
7thfName: heptaglutamyl folate (THF)
Formula: C49H57N13O24
Charge: -8




click to see details on this item[m]
7thfName: heptaglutamyl folate (THF)
Formula: C49H57N13O24
Charge: -8




click to see details on this item[c]
Not determined
Transport
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