Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	fa8p1n3coa
Name .....................................................	:	Intermediary fatty acid C8:1
Model ID .....................................................	:	CC0091
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	Not available
Formula .....................................................	:	C29H44N7O17P3S
Charge .....................................................	:	-4
Localization .....................................................	:	Cytosol, Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	Not available
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Mitochondrial fatty acid degradation (c,m), Peroxisomal fatty acid degradation (c)

iCEL1314

Comments

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0099Name: Acyl-CoA:L-carnitine O-acyltransferase I (intermediary fatty acyl [C8:1]-CoA) Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	2.3.1.137Name: carnitine O-octanoyltransferase Other names: medium-chain/long-chain carnitine acyltransferase, carnitine medium-chain acyltransferase, easily solubilized mitochondrial carnitine palmitoyltransferase, overt mitochondrial carnitine palmitoyltransferase click to see details on this item	[c] : crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa8p1n3coaName: Intermediary fatty acid C8:1 Formula: C29H44N7O17P3S Charge: -4 click to see details on this item		coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa8p1n3crnName: Fatty acyl C8:1 carnitine Formula: C15H27NO4 Charge: 0 click to see details on this item	F41E7.6 | T20B3.1	Mitochondrial fatty acid degradation
RMC0099Name: Acyl-CoA:L-carnitine O-acyltransferase II (intermediary fatty acyl [C8:1]-CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa8p1n3crnName: Fatty acyl C8:1 carnitine Formula: C15H27NO4 Charge: 0 click to see details on this item		crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa8p1n3coaName: Intermediary fatty acid C8:1 Formula: C29H44N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0097Name: Beta oxidation of intermediary fatty acid C16:4 (mitochondrial) Type: Regular Location: Mitochondria KEGG ID: R00392;R04319;R03224;R02685;R01778;R00391 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item 5.3.3.8Name: dodecenoyl-CoA isomerase Other names: dodecenoyl-CoA Delta-isomerase, Delta3-cis-Delta2-trans-enoyl-CoA isomerase, acetylene-allene isomerase, dodecenoyl-CoA Delta-isomerase, dodecenoyl-CoA Delta3-cis-Delta2-trans-isomerase click to see details on this item 1.3.1.34Name: 2,4-dienoyl-CoA reductase (NADPH) Other names: 4-enoyl-CoA reductase (NADPH), 4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase, 4-enoyl-CoA reductase, 2,4-dienoyl-CoA reductase (NADPH) click to see details on this item 4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item 1.1.1.211Name: long-chain-3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, LCHAD click to see details on this item 1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item 2.3.1.16Name: acetyl-CoA C-acyltransferase Other names: beta-ketothiolase, 3-ketoacyl-CoA thiolase, KAT, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 6-oxoacyl-CoA thiolase, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, pro-3-ketoacyl-CoA thiolase, thiolase I, 2-methylacetoacetyl-CoA thiolase [misleading] click to see details on this item	[m] : (4) coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (4) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (4) nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + (3) fadName: Flavin adenine dinucleotide oxidized Formula: C27H31N9O15P2 Charge: -2 click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + fa16p4n3coaName: Intermediary fatty acid C16:4 Formula: C37H54N7O17P3S Charge: -4 click to see details on this item		(4) accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + (3) fadh2Name: Flavin adenine dinucleotide reduced Formula: C27H33N9O15P2 Charge: -2 click to see details on this item + (4) nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + fa8p1n3coaName: Intermediary fatty acid C8:1 Formula: C29H44N7O17P3S Charge: -4 click to see details on this item	(acdh-7 | acdh-8 | acdh-10 | acdh-12) & (ech-4 | B0272.4) & (decr-1.2 | decr-1.3) & [(ech-6 | ech-7) | (ech-1.2 | ech-1.1) | ech-3] & [(ech-1.2 | ech-1.1) | (B0272.3 | F54C8.1 | ech-8 | ech-9 | hacd-1)] & (B0303.3 | acaa-2)	Mitochondrial fatty acid degradation
RMC0100Name: Beta oxidation of intermediary fatty acid fa8p1n3 Type: Regular Location: Mitochondria KEGG ID: R00392;R02685;R01778;R00391 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item 5.3.3.8Name: dodecenoyl-CoA isomerase Other names: dodecenoyl-CoA Delta-isomerase, Delta3-cis-Delta2-trans-enoyl-CoA isomerase, acetylene-allene isomerase, dodecenoyl-CoA Delta-isomerase, dodecenoyl-CoA Delta3-cis-Delta2-trans-isomerase click to see details on this item 4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item 1.1.1.211Name: long-chain-3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, LCHAD click to see details on this item 1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item 2.3.1.16Name: acetyl-CoA C-acyltransferase Other names: beta-ketothiolase, 3-ketoacyl-CoA thiolase, KAT, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 6-oxoacyl-CoA thiolase, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, pro-3-ketoacyl-CoA thiolase, thiolase I, 2-methylacetoacetyl-CoA thiolase [misleading] click to see details on this item	[m] : (2) coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (2) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (2) nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + fadName: Flavin adenine dinucleotide oxidized Formula: C27H31N9O15P2 Charge: -2 click to see details on this item + fa8p1n3coaName: Intermediary fatty acid C8:1 Formula: C29H44N7O17P3S Charge: -4 click to see details on this item		(2) accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + fadh2Name: Flavin adenine dinucleotide reduced Formula: C27H33N9O15P2 Charge: -2 click to see details on this item + (2) nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + btcoaName: Butanoyl-CoA Formula: C25H38N7O17P3S Charge: -4 click to see details on this item	(acdh-7 | acdh-8 | acdh-10) & (ech-4 | B0272.4) & [(ech-6 | ech-7) | (ech-1.2 | ech-1.1) | ech-3] & [(ech-1.2 | ech-1.1) | (B0272.3 | F54C8.1 | ech-8 | ech-9 | hacd-1)] & (B0303.3 | acaa-2)	Mitochondrial fatty acid degradation
RCC0097Name: Beta oxidation of intermediary fatty acid C16:4 (peroxisomal) Type: Regular Location: Cytosol KEGG ID: R00388;R04319;R03224;R02685;R01778;R00391 click to see details on this item	1.3.3.6Name: acyl-CoA oxidase Other names: fatty acyl-CoA oxidase, acyl coenzyme A oxidase, fatty acyl-coenzyme A oxidase click to see details on this item 5.3.3.8Name: dodecenoyl-CoA isomerase Other names: dodecenoyl-CoA Delta-isomerase, Delta3-cis-Delta2-trans-enoyl-CoA isomerase, acetylene-allene isomerase, dodecenoyl-CoA Delta-isomerase, dodecenoyl-CoA Delta3-cis-Delta2-trans-isomerase click to see details on this item 1.3.1.34Name: 2,4-dienoyl-CoA reductase (NADPH) Other names: 4-enoyl-CoA reductase (NADPH), 4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase, 4-enoyl-CoA reductase, 2,4-dienoyl-CoA reductase (NADPH) click to see details on this item 4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item 1.1.1.211Name: long-chain-3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, LCHAD click to see details on this item 1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item 2.3.1.16Name: acetyl-CoA C-acyltransferase Other names: beta-ketothiolase, 3-ketoacyl-CoA thiolase, KAT, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 6-oxoacyl-CoA thiolase, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, pro-3-ketoacyl-CoA thiolase, thiolase I, 2-methylacetoacetyl-CoA thiolase [misleading] click to see details on this item	[c] : (4) coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (4) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (4) nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + (3) o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + fa16p4n3coaName: Intermediary fatty acid C16:4 Formula: C37H54N7O17P3S Charge: -4 click to see details on this item		(4) accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + (3) h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + (4) nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + fa8p1n3coaName: Intermediary fatty acid C8:1 Formula: C29H44N7O17P3S Charge: -4 click to see details on this item	(acox-1.5 | acox-1.1 | acox-1.2 | acox-1.3 | acox-1.4 | acox-3 | acox-1.6) & F58A6.1 & F53C11.3 & (dhs-28 | maoc-1) & daf-22	Peroxisomal fatty acid degradation

The information and tools provided in this website are to be used for academic purposes only. Potential users of the flux analysis tools (FBA button in the vertical menu) are asked to show proof of working at an academic institution during the creation of their accounts. These mathematical tools are powered by the commercial software Gurobi.