WormFlux: mechanistic analysis of C. elegans metabolism

Gene Overview

Name .....................................................	:	cpt-2
Sequence ID .....................................................	:	R07H5.2
Status (?) Can be one of the following two: Curated (manually annotated or based on a curated SACURE result), or Not curated (SACURE result reported without manual check). .....................................................	:	Curated
KO (?) The KEGG orthology group (KO) that is associated with this gene. .....................................................	:	K08766CPT2; carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
Enzymes in the model (?) Enzymes that are part of the current metabolic network model. .....................................................	:	2.3.1.21names: carnitine O-palmitoyltransferase;CPT;CPTo;outer malonyl-CoA inhibitable carnitine palmitoyltransferase;CPTi;CPT I (outer membrane carnitine palmitoyl transferase);carnitine palmitoyltransferase I;carnitine palmitoyltransferase II;CPT-A;CPT-B;acylcarnitine transferase;carnitine palmitoyltransferase;carnitine palmitoyltransferase-A;L-carnitine palmitoyltransferase;palmitoylcarnitine transferase, 2.3.1.7names: carnitine O-acetyltransferase;acetyl-CoA-carnitine O-acetyltransferase;acetylcarnitine transferase;carnitine acetyl coenzyme A transferase;carnitine acetylase;carnitine acetyltransferase;carnitine-acetyl-CoA transferase;CATC
Other enzymes (?) Enzymes that are associated with this gene in the WormFlux database, but not included in the current network model. .....................................................	:	None
Model reactions (?) Reactions that are part of the current metabolic network model. See the bottom of this page for a table of reactions. .....................................................	:	RMC0099, RMC0122, RMC0123, RMC0120, RMC0121, RM01923, RMC0087, RMC0108, RMC0109, RMC0119, RMC0118, RMC0117, RMC0116, RMC0115, RMC0114, RMC0113, RMC0112, RMC0111, RMC0110, RMC0058, RMC0154, RM02396
Relevant model reactions (?) Model reactions that follow from the KEGG reactions associated with this gene, but that exclude this gene due to differences in reaction specificity or localization compared to the predictions for this gene. .....................................................	:	ERROR
Other reactions (?) KEGG reactions that are associated with this gene in the WormFlux database, but not included in the current network model. .....................................................	:	None

In WormPaths (?) Pathway maps where this gene is represented are listed here. .....................................................	:	Mitochondrial fatty acid degradation, Propionate degradation

External links

WBGene00011122

CELE_R07H5.2

G5EFE6 G5ECS9

► | Gene-KO-Enzyme-Reaction Associations (click to view)▼ | Gene-KO-Enzyme-Reaction Associations (click to hide)

SACURE (?) Associations established by SACURE (Systematic Annotation by CUration and REgression).

SACURE pipeline annotates genes based on a logistic function that converts evidence from multiple resources into a KEGG orthology decision, which is then associated with enzymes and reactions. False positives and false negatives of the logistic function are separated out during manual curation for making exceptional decisions.

See HELP in the upper menu for a description of the SACURE pipeline.

See below for a summary of association scores from SACURE.

Results (?) KO: Associated KEGG Orthology groups
Enzyme: Associated enzymes in EC numbering
Reactions: Associated reactions from KEGG reaction database.

Confidence level is indicated for each association as a function of overall SACURE score (a probability of true association; see below in the SACURE scores section). Score ranges for HIGH, MEDIUM, and LOW confidence levels are >0.99, 0.90-0.99, and 0.50-0.90, respectively. If an association is accepted with a probability less than 0.50 (due to an exceptional reason), then the confidence level is LOW.

Not determined indicates that annotation analysis resulted in no clear associations.

	ID - Confidence
KO	K08766 - High
Enzyme	2.3.1.21 - High
Reaction	R01923 - High

Comments

Based on the logistic function.
See scores from predictors and the logistic function below (SACURE summary).

Reconstruction (?) Associations established during the reconstruction process by lenient annotation, literature search, or gap-filling.

Results (?) KO: Associated KEGG Orthology groups
Enzyme: Associated enzymes in EC numbering
Reactions: Associated reactions from KEGG reaction database or custom reactions developed during reconstruction.

	ID - Confidence
KO	Not determined
Enzyme	2.3.1.7 - Low
Reaction	R02396 - Low RMC0058 - Low RMC0087 - Low RMC0099 - Low RMC0108 - Low RMC0109 - Low RMC0110 - Low RMC0111 - Low RMC0112 - Low RMC0113 - Low RMC0114 - Low RMC0115 - Low RMC0116 - Low RMC0117 - Low RMC0118 - Low RMC0119 - Low RMC0120 - Low RMC0121 - Low RMC0122 - Low RMC0123 - Low RMC0154 - Low

Comments

Based on homology and protein localization, cpt-2 is the only candidate gene found to carry out the mitochondrial part of carnitine shuttle.

► | SACURE Summary (click to view)▼ | SACURE scores (click to hide)

Score table (?) Association scores for KOs best matching to the query gene according to each annotation predictor, and for the accepted KO if there is any (rightmost columns).

The predictors are ordered in decreasing weight of contribution to the decision-making process in SACURE.

See above for the final decision on the annotation of this gene.

Predictor	Best scoring KOs	Best score	K08766	ERROR
KEGG (?) Score represents the annotation in KEGG database by June 2014. Takes a value of either 0 (KO is not associated with the query gene) or 1 (KO is associated with the query gene).	K08766	1	1	ERROR
Cluster (?) Score represents the degree of relatedness of a KO to the query gene based on the clustering in the phylogenetic tree of protein sequences (see below for the tree). Takes values from 0 to 1.	K08766	1.00	1.00	ERROR
myKEGG (?) Score represents the degree of relatedness of a KO to the query gene based on the Smith-Waterman alignment of protein sequence with most similar sequences from all organisms in the KEGG database. Takes values from 0 to 1. KOunknown indicates the score for sequences without any KO association in KEGG database.	K08766	0.92	0.92	ERROR
Tree (?) Score shows the degree of relatedness of a KO to the query gene based on the density of this KO in the phylogenetic tree of protein sequences (see below for the tree). Takes values from 0 to 2 as the score is normalized to the second best KO. KOunknown indicates the score for sequences without any KO association in KEGG database.	K08766	1.90	1.90	ERROR
KOG (?) Score indicates the absence or presence of a KO in association with one of the orthologs of the query gene according to a eukaryotic orthology database independent of KEGG (see HELP* in the upper menu for details). Takes a value of either 0 (absent) or 1 (present*).	K08766 K00624 and 1 more...All best scoring KOs: K08766, K00624, K08765	1	1	ERROR
WormBase (?) Score represents matching between the KEGG descriptions of a KO (KO name and all related enzyme names) and the descriptions of the query gene in WormBase (gene overview and protein domains). Value is increased by 0.5 for every perfect word match and reduced by 0.1 for each character interruption. A non-matching word always creates a 0 score. WormBase description used for this gene was: "Acyltransferase ChoActase/COT/CPT $ Calponin-like actin-binding $ Choline/Carnitine o-acyltransferase $$ cpt-2 encodes a carnitine palmitoyltranferase orthologous to the human gene CPT2, an enzyme involved in fatty acid oxidation."	K08766 K13644 and 6 more...All best scoring KOs: K08766, K13644, K08765, K13664, K13663, K00994, K05996, K16036	0.5	0.5	ERROR
Overall (?) Overall score from SACURE that represents the logistic-regression-based probability of acceptance of a KO in association with the query gene.	K08766	1.000	1.000	ERROR

► | Localization scores (click to view)▼ | Localization scores (click to hide)

Score table (?) Localization scores for proteins encoded by the query gene.

Each predictor is used to determine whether the protein is localized to mitochondria or other compartment.

Together with other genes and other predictors, these scores were used in the determination of the subcellular location of reactions associated with the query gene (see below for the reactions).

Predictor	Mitochondrial	Other
Mitoprot (?) Score represents the predicted probability that the protein is targeted to mitochondria (mitochondrial score) or not (other score) according to Mitoprot (click to reach). If multiple isofoms of the same protein are available the highest scores are shown for each compartment.	0.88	0.22
MitoMiner (?) Score evaluates the evidence for mitochondrial targeting based on the orthologs in 12 eukaryotic model organisms that are in the MitoMiner database (click to reach). If clear orthologs for the query gene are available in MitoMiner organisms, the score takes a value between 0 and 1 as a function of the ratio of orthologs that have hits (contributes to the mitochondrial score) or no hits (determines the other score) in the database. Mitochondrial score is also a function of the strength of the evidence for the orthologs found in the database (experimental evidence is given a higher weight than theoretical evidence during scoring).	0.97	0.00
UniProt (?) Score shows the subcellular localization of proteins encoded by this gene as reported in UniProt (click to reach) in October 2014. If a report is available, the score takes a value of either 0 (not reported to be localized to the pertaining compartment) or 1 (reported to be localized to the pertaining compartment).	Not available	Not available
Org. DB (?) Score shows the subcellular localization of proteins encoded by this gene as reported in Organelle Database (click to reach). If a report is available, the score takes a value of either 0 (not reported to be localized to the pertaining compartment) or 1 (reported to be localized to the pertaining compartment).	Not available	Not available

► | Phylogenetic tree (click to view)▼ | Phylogenetic tree (click to hide)

(?) Phylogenetic tree of protein sequences including the query gene, nearest matches in selected organisms from different taxonomic groups, and paralogs in C. elegans. All sequences are obtained from KEGG database.

This figure is interactive, click items to reach relevant KEGG pages.

A low number of orthologs represented on this tree indicates the lack of similar sequences in other organisms.

See below for the legend.

Sequence labels indicate KO, taxonomy or model organism, organism name (if taxonomic group), and gene name, respectively. CEL, C. elegans; HSA, H. sapiens; DME, D. melanogaster; ATH, A. thaliana; SCE, S. cerevisiae; BAC, bacteria; ARC, archaea; PRO, protists; FUN, fungi; PLA, plants; INV, invertebrates; NEM, nematodes; ART, arthropods; VER, vertebrates; MAM, mammals. Parenthetical information for organisms other than CEL indicates whether the genes are introduced as best matches (B) or reciprocal best hits (R) to the query gene. Parenthetical information for CEL indicates whether the genes are introduced as paralogues (P) of the query gene or as reciprocal best matches to one of the other organisms in the tree (B). Organism abbreviations are from KEGG.

Reactions

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RMC0099Name: Acyl-CoA:L-carnitine O-acyltransferase II (intermediary fatty acyl [C8:1]-CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa8p1n3crnName: Fatty acyl C8:1 carnitine Formula: C15H27NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa8p1n3coaName: Intermediary fatty acid C8:1 Formula: C29H44N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0122Name: Acyl-CoA:L-carnitine O-acyltransferase II (Fatty acyl [C17:iso] CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa17p0isocrnName: Fatty acyl (C17:iso) carnitine Formula: C24H47NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa17p0isocoaName: Fatty acyl (C17:iso) coa Formula: C38H64N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0123Name: Acyl-CoA:L-carnitine O-acyltransferase II (Fatty acyl [C9:iso] CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa9p0isocrnName: Fatty acyl (C9:iso) carnitine Formula: C16H31NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa9p0isocoaName: Fatty acyl (C9:iso) coa Formula: C30H48N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0120Name: Acyl-CoA:L-carnitine O-acyltransferase II (cis-11,12-methyleneoctadecanoyl-CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa19c11crnName: cis-11,12-methyleneoctadecanoyl carnitine Formula: C26H49NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa19c11coaName: cis-11,12-methyleneoctadecanoyl coa Formula: C40H66N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0121Name: Acyl-CoA:L-carnitine O-acyltransferase II (Fatty acyl [C15:iso] CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa15p0isocrnName: Fatty acyl (C15:iso) carnitine Formula: C22H43NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa15p0isocoaName: Fatty acyl (C15:iso) coa Formula: C36H60N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RM01923Name: Palmitoyl-CoA:L-carnitine O-palmitoyltransferase II Type: Regular Location: Mitochondria KEGG ID: R01923 click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + pmtcrnName: L-Palmitoylcarnitine Formula: C23H45NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + pmtcoaName: Palmitoyl-CoA (n-C16:0CoA) Formula: C37H62N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0087Name: Acyl-CoA:L-carnitine O-acyltransferase II (Octanoyl-CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + occrnName: Octanoyl carnitine Formula: C15H29NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + occoaName: Octanoyl-CoA (n-C8:0CoA) Formula: C29H46N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0108Name: Acyl-CoA:L-carnitine O-acyltransferase II (vaccenyl CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + vacccrnName: Vaccenyl carnitine Formula: C25H47NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + vacccoaName: Vaccenyl coenzyme A Formula: C39H64N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0109Name: Acyl-CoA:L-carnitine O-acyltransferase II (Octadecenoyl-CoA ) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + odecrnName: Octadecenoyl carnitine Formula: C25H47NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + odecoaName: Octadecenoyl-CoA (n-C18:1CoA) Formula: C39H64N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0119Name: Acyl-CoA:L-carnitine O-acyltransferase II (cis-9,10-methylenehexadecanoyl-CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa17c9crnName: cis-9,10-methylenehexadecanoyl carnitine Formula: C24H45NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa17c9coaName: cis-9,10-methylenehexadecanoyl coa Formula: C38H62N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0118Name: Acyl-CoA:L-carnitine O-acyltransferase II (cis-3,4-methylenedecanoyl-CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa11c3crnName: cis-3,4-methylenedecanoyl coa Formula: C18H33NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa11c3coaName: cis-3,4-methylenedecanoyl coa Formula: C32H50N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0117Name: Acyl-CoA:L-carnitine O-acyltransferase II (Palmitoleyl-CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa16p1n7crnName: Palmitoleyl carnitine Formula: C23H43NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + fa16p1n7coaName: Palmitoleyl-coA Formula: C37H60N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0116Name: Acyl-CoA:L-carnitine O-acyltransferase II (Stearoyl-CoA ) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + stcrnName: Stearoylcarnitine Formula: C25H49NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + stcoaName: Stearoyl-CoA (n-C18:0CoA) Formula: C39H66N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0115Name: Acyl-CoA:L-carnitine O-acyltransferase II (Tetradecanoyl-CoA ) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + ttdcrnName: tetradecanoyl carnitine Formula: C21H41NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + tdcoaName: Tetradecanoyl-CoA (n-C14:0CoA) Formula: C35H58N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0114Name: Acyl-CoA:L-carnitine O-acyltransferase II (fatty acyl [C20:4]-CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + arachdcrnName: C20:4 carnitine Formula: C27H45NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + arachdcoaName: C20:4-CoA Formula: C41H62N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0113Name: Acyl-CoA:L-carnitine O-acyltransferase II (eicosatetranoyl CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + eicostetcrnName: Eicosatetranoyl carnitine Formula: C27H45NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + eicostetcoaName: eicosatetranoyl coenzyme A Formula: C41H62N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0112Name: Acyl-CoA:L-carnitine O-acyltransferase II (timnodonyl CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + tmndnccrnName: Timnodonyl carnitine Formula: C27H43NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + tmndnccoaName: timnodonyl coenzyme A Formula: C41H60N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0111Name: Acyl-CoA:L-carnitine O-acyltransferase II (dihomo-gamma-linolenyl CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + dlnlcgcrnName: dihomo-gamma-linolenyl carnitine Formula: C27H47NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + dlnlcgcoaName: dihomo-gamma-linolenyl coenzyme A Formula: C41H64N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0110Name: Acyl-CoA:L-carnitine O-acyltransferase II (linoleic CoA) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + lnlccrnName: Linoleyl carnitine Formula: C25H45NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + lnlccoaName: linoleic coenzyme A Formula: C39H62N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0058Name: Acyl-CoA:L-carnitine O-acyltransferase II (Dodecanoyl-CoA ) Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.21Name: carnitine O-palmitoyltransferase Other names: CPT, CPTo, outer malonyl-CoA inhibitable carnitine palmitoyltransferase, CPTi, CPT I (outer membrane carnitine palmitoyl transferase), carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, CPT-A, CPT-B, acylcarnitine transferase, carnitine palmitoyltransferase, carnitine palmitoyltransferase-A, L-carnitine palmitoyltransferase, palmitoylcarnitine transferase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + ddcrnName: dodecanoyl carnitine Formula: C19H37NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + ddcacoaName: Dodecanoyl-CoA (n-C12:0CoA) Formula: C33H54N7O17P3S Charge: -4 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation
RMC0154Name: Propionyl-CoA:carnitine O-propionyltransferase II Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	2.3.1.7Name: carnitine O-acetyltransferase Other names: acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine transferase, carnitine acetyl coenzyme A transferase, carnitine acetylase, carnitine acetyltransferase, carnitine-acetyl-CoA transferase, CATC click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + pcrnName: Propionyl-carnitine Formula: C10H19NO4 Charge: 0 click to see details on this item	crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + ppcoaName: Propanoyl-CoA Formula: C24H36N7O17P3S Charge: -4 click to see details on this item	cpt-2	Miscellaneous
RM02396Name: Acetyl-CoA:carnitine O-acetyltransferase II Type: Regular Location: Mitochondria KEGG ID: R02396 click to see details on this item	2.3.1.7Name: carnitine O-acetyltransferase Other names: acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine transferase, carnitine acetyl coenzyme A transferase, carnitine acetylase, carnitine acetyltransferase, carnitine-acetyl-CoA transferase, CATC click to see details on this item	[m] : acrnName: O-Acetylcarnitine Formula: C9H17NO4 Charge: 0 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item	accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item	cpt-2	Mitochondrial fatty acid degradation

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