Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	1.6.5.3
Name .....................................................	:	NADH:ubiquinone reductase (H+-translocating), etc.Ubiquinone reductase, Type 1 dehydrogenase, Complex 1 dehydrogenase, Coenzyme Q reductase, Complex I (electron transport chain), Complex I (mitochondrial electron transport), Complex I (NADH:Q1 oxidoreductase), Dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, Mitochondrial electron transport complex 1, Mitochondrial electron transport complex I, NADH coenzyme Q1 reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase, NADH-ubiquinone reductase, NADH-ubiquinone oxidoreductase, NADH-ubiquinone-1 reductase, Reduced nicotinamide adenine dinucleotide-coenzyme Q reductase, NADH:ubiquinone oxidoreductase complex, NADH-Q6 oxidoreductase, Electron transfer complex I, NADH2 dehydrogenase (ubiquinone)
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K03961NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5, K03960NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4, K03949NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5, K03962NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6, K03965NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9, K03964NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8, K03966NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10, K03943NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3], K03968NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2, K03941NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3], K03940NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3], K03946NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2, K03945NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1, K03942NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3], K03884ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:1.6.5.3], K03882ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:1.6.5.3], K03883ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:1.6.5.3], K03880ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:1.6.5.3], K03881ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:1.6.5.3], K03963NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7, K11351NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11, K11353NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13, K03879ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:1.6.5.3], K03878ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:1.6.5.3], K03958NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2, K03959NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3, K03954NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10, K03955NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, K03950NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6, K03951NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7, K03952NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8, K03953NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9, K03938NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5, K03939NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6, K03936NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3], K03937NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4, K03934NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3], K03935NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
Genes .....................................................	:	C16A3.5, C18E9.4, C25H3.9, C33A12.1, C34B2.8, D2030.4, F31D4.9, F37C12.3, F42G8.10, F44G4.2, F45H10.3, F53F4.10, F59C6.5, T20H4.5, Y51H1A.3, Y53G8AL.2, Y54F10AM.5, Y56A3A.19, Y63D3A.7, Y71H2AM.4, ZK809.3, gas-1, lpd-5, ndfl-4, nduf-2.2, nduf-5, nduf-6, nduf-7, nduo-1, nduo-2, nduo-3, nduo-4, nduo-5, nduo-6, nuo-1, nuo-2, nuo-3, nuo-4, nuo-5, nuo-6
Localization .....................................................	:	Cytosol, Mitochondria
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RMC0006Name: NADH:ubiquinone oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: R02163 click to see details on this item	1.6.5.3Name: NADH:ubiquinone reductase (H+-translocating) Other names: ubiquinone reductase, type 1 dehydrogenase, complex 1 dehydrogenase, coenzyme Q reductase, complex I (electron transport chain), complex I (mitochondrial electron transport), complex I (NADH:Q1 oxidoreductase), dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, mitochondrial electron transport complex 1, mitochondrial electron transport complex I, NADH coenzyme Q1 reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase, NADH-ubiquinone reductase, NADH-ubiquinone oxidoreductase, NADH-ubiquinone-1 reductase, reduced nicotinamide adenine dinucleotide-coenzyme Q reductase, NADH:ubiquinone oxidoreductase complex, NADH-Q6 oxidoreductase, electron transfer complex I, NADH2 dehydrogenase (ubiquinone) click to see details on this item 1.6.99.3Name: NADH dehydrogenase Other names: cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase, dihydrocodehydrogenase I dehydrogenase, dihydronicotinamide adenine dinucleotide dehydrogenase, diphosphopyridine diaphorase, DPNH diaphorase, NADH diaphorase, NADH hydrogenase, NADH oxidoreductase, NADH-menadione oxidoreductase, reduced diphosphopyridine nucleotide diaphorase, NADH:cytochrome c oxidoreductase, NADH2 dehydrogenase, NADH:(acceptor) oxidoreductase click to see details on this item	qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item[m] + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item[m] + (5.0) hName: H+ Formula: H Charge: 1 click to see details on this item[m]		qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item[m] + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item[m] + (4.0) hName: H+ Formula: H Charge: 1 click to see details on this item[c]	(nduo-1 & nduo-2 & nduo-3 & nduo-4 & nduo-5 & nduo-6 & ndfl-4) & [F53F4.10 & (gas-1 | nduf-2.2) & nuo-2 & nuo-1 & nuo-5 & nduf-7 & T20H4.5 & lpd-5 & nduf-5 & nduf-6] & [F31D4.9 & Y63D3A.7 & C33A12.1 & nuo-3 & F45H10.3 & Y54F10AM.5 & Y53G8AL.2 & nuo-4 & (F37C12.3 | Y56A3A.19) & C34B2.8] & (F44G4.2 & C18E9.4 & nuo-6 & C25H3.9 & ZK809.3 & D2030.4 & Y51H1A.3 & C16A3.5 & F59C6.5 & Y71H2AM.4 & F42G8.10)	Electron transport chain
RMC0007Name: NADH:ubiquinone oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: R02163 click to see details on this item	1.6.5.3Name: NADH:ubiquinone reductase (H+-translocating) Other names: ubiquinone reductase, type 1 dehydrogenase, complex 1 dehydrogenase, coenzyme Q reductase, complex I (electron transport chain), complex I (mitochondrial electron transport), complex I (NADH:Q1 oxidoreductase), dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, mitochondrial electron transport complex 1, mitochondrial electron transport complex I, NADH coenzyme Q1 reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase, NADH-ubiquinone reductase, NADH-ubiquinone oxidoreductase, NADH-ubiquinone-1 reductase, reduced nicotinamide adenine dinucleotide-coenzyme Q reductase, NADH:ubiquinone oxidoreductase complex, NADH-Q6 oxidoreductase, electron transfer complex I, NADH2 dehydrogenase (ubiquinone) click to see details on this item 1.6.99.3Name: NADH dehydrogenase Other names: cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase, dihydrocodehydrogenase I dehydrogenase, dihydronicotinamide adenine dinucleotide dehydrogenase, diphosphopyridine diaphorase, DPNH diaphorase, NADH diaphorase, NADH hydrogenase, NADH oxidoreductase, NADH-menadione oxidoreductase, reduced diphosphopyridine nucleotide diaphorase, NADH:cytochrome c oxidoreductase, NADH2 dehydrogenase, NADH:(acceptor) oxidoreductase click to see details on this item	qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item[m] + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item[m] + hName: H+ Formula: H Charge: 1 click to see details on this item[c]		qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item[m] + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item[m]	(nduo-1 & nduo-2 & nduo-3 & nduo-4 & nduo-5 & nduo-6 & ndfl-4) & [F53F4.10 & (gas-1 | nduf-2.2) & nuo-2 & nuo-1 & nuo-5 & nduf-7 & T20H4.5 & lpd-5 & nduf-5 & nduf-6] & [F31D4.9 & Y63D3A.7 & C33A12.1 & nuo-3 & F45H10.3 & Y54F10AM.5 & Y53G8AL.2 & nuo-4 & (F37C12.3 | Y56A3A.19) & C34B2.8] & (F44G4.2 & C18E9.4 & nuo-6 & C25H3.9 & ZK809.3 & D2030.4 & Y51H1A.3 & C16A3.5 & F59C6.5 & Y71H2AM.4 & F42G8.10)	Electron transport chain
RMC0008Name: NADH:ubiquinone oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R02163 click to see details on this item	1.6.5.3Name: NADH:ubiquinone reductase (H+-translocating) Other names: ubiquinone reductase, type 1 dehydrogenase, complex 1 dehydrogenase, coenzyme Q reductase, complex I (electron transport chain), complex I (mitochondrial electron transport), complex I (NADH:Q1 oxidoreductase), dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, mitochondrial electron transport complex 1, mitochondrial electron transport complex I, NADH coenzyme Q1 reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase, NADH-ubiquinone reductase, NADH-ubiquinone oxidoreductase, NADH-ubiquinone-1 reductase, reduced nicotinamide adenine dinucleotide-coenzyme Q reductase, NADH:ubiquinone oxidoreductase complex, NADH-Q6 oxidoreductase, electron transfer complex I, NADH2 dehydrogenase (ubiquinone) click to see details on this item 1.6.99.3Name: NADH dehydrogenase Other names: cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase, dihydrocodehydrogenase I dehydrogenase, dihydronicotinamide adenine dinucleotide dehydrogenase, diphosphopyridine diaphorase, DPNH diaphorase, NADH diaphorase, NADH hydrogenase, NADH oxidoreductase, NADH-menadione oxidoreductase, reduced diphosphopyridine nucleotide diaphorase, NADH:cytochrome c oxidoreductase, NADH2 dehydrogenase, NADH:(acceptor) oxidoreductase click to see details on this item	[m] : qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	(nduo-1 & nduo-2 & nduo-3 & nduo-4 & nduo-5 & nduo-6 & ndfl-4) & [F53F4.10 & (gas-1 | nduf-2.2) & nuo-2 & nuo-1 & nuo-5 & nduf-7 & T20H4.5 & lpd-5 & nduf-5 & nduf-6] & [F31D4.9 & Y63D3A.7 & C33A12.1 & nuo-3 & F45H10.3 & Y54F10AM.5 & Y53G8AL.2 & nuo-4 & (F37C12.3 | Y56A3A.19) & C34B2.8] & (F44G4.2 & C18E9.4 & nuo-6 & C25H3.9 & ZK809.3 & D2030.4 & Y51H1A.3 & C16A3.5 & F59C6.5 & Y71H2AM.4 & F42G8.10)	Electron transport chain
RMC0184Name: NADH:rhodoquinone oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: R00281 click to see details on this item	1.6.5.3Name: NADH:ubiquinone reductase (H+-translocating) Other names: ubiquinone reductase, type 1 dehydrogenase, complex 1 dehydrogenase, coenzyme Q reductase, complex I (electron transport chain), complex I (mitochondrial electron transport), complex I (NADH:Q1 oxidoreductase), dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, mitochondrial electron transport complex 1, mitochondrial electron transport complex I, NADH coenzyme Q1 reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase, NADH-ubiquinone reductase, NADH-ubiquinone oxidoreductase, NADH-ubiquinone-1 reductase, reduced nicotinamide adenine dinucleotide-coenzyme Q reductase, NADH:ubiquinone oxidoreductase complex, NADH-Q6 oxidoreductase, electron transfer complex I, NADH2 dehydrogenase (ubiquinone) click to see details on this item 1.6.99.3Name: NADH dehydrogenase Other names: cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase, dihydrocodehydrogenase I dehydrogenase, dihydronicotinamide adenine dinucleotide dehydrogenase, diphosphopyridine diaphorase, DPNH diaphorase, NADH diaphorase, NADH hydrogenase, NADH oxidoreductase, NADH-menadione oxidoreductase, reduced diphosphopyridine nucleotide diaphorase, NADH:cytochrome c oxidoreductase, NADH2 dehydrogenase, NADH:(acceptor) oxidoreductase click to see details on this item	rq9Name: Rhodoquinone-9 Formula: C53H81NO3 Charge: 0 click to see details on this item[m] + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item[m] + (5.0) hName: H+ Formula: H Charge: 1 click to see details on this item[m]		rq9h2Name: Rhodoquinonol-9 Formula: C53H83NO3 Charge: 0 click to see details on this item[m] + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item[m] + (4.0) hName: H+ Formula: H Charge: 1 click to see details on this item[c]	(nduo-1 & nduo-2 & nduo-3 & nduo-4 & nduo-5 & nduo-6 & ndfl-4) & [F53F4.10 & (gas-1 | nduf-2.2) & nuo-2 & nuo-1 & nuo-5 & nduf-7 & T20H4.5 & lpd-5 & nduf-5 & nduf-6] & [F31D4.9 & Y63D3A.7 & C33A12.1 & nuo-3 & F45H10.3 & Y54F10AM.5 & Y53G8AL.2 & nuo-4 & (F37C12.3 | Y56A3A.19) & C34B2.8] & (F44G4.2 & C18E9.4 & nuo-6 & C25H3.9 & ZK809.3 & D2030.4 & Y51H1A.3 & C16A3.5 & F59C6.5 & Y71H2AM.4 & F42G8.10)	Electron transport chain

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