WormFlux: mechanistic analysis of C. elegans metabolism

(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	3.6.1.19
Name .....................................................	:	Nucleoside-triphosphate diphosphatase, etc.Nucleoside-triphosphate pyrophosphatase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K01519ITPA; inosine triphosphate pyrophosphatase [EC:3.6.1.19]
Genes .....................................................	:	hap-1
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below.

External links

KEGG

BRENDA

Reactions

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00720Name: Inosine 5-triphosphate pyrophosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00720 click to see details on this item	3.6.1.19Name: nucleoside-triphosphate diphosphatase Other names: nucleoside-triphosphate pyrophosphatase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + itpName: ITP Formula: C10H11N4O14P3 Charge: -4 click to see details on this item	hName: H+ Formula: H Charge: 1 click to see details on this item + impName: IMP Formula: C10H11N4O8P Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	hap-1	Purine metabolism
RC00426Name: GTP diphosphohydrolase (diphosphate-forming) Type: Regular Location: Cytosol KEGG ID: R00426 click to see details on this item	3.6.1.19Name: nucleoside-triphosphate diphosphatase Other names: nucleoside-triphosphate pyrophosphatase click to see details on this item	[c] : gtpName: GTP Formula: C10H12N5O14P3 Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	gmpName: GMP Formula: C10H12N5O8P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	hap-1	Purine metabolism
RC01855Name: 2-Deoxyguanosine 5-triphosphate diphosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01855 click to see details on this item	3.6.1.19Name: nucleoside-triphosphate diphosphatase Other names: nucleoside-triphosphate pyrophosphatase click to see details on this item	[c] : dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	dgmpName: dGMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	hap-1	Purine metabolism
RC00662Name: Uridine triphosphate pyrophosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00662 click to see details on this item	3.6.1.19Name: nucleoside-triphosphate diphosphatase Other names: nucleoside-triphosphate pyrophosphatase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + utpName: UTP Formula: C9H11N2O15P3 Charge: -4 click to see details on this item	hName: H+ Formula: H Charge: 1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item + umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item	hap-1	Pyrimidine metabolism
RC02100Name: dUTP nucleotidohydrolase Type: Regular Location: Cytosol KEGG ID: R02100 click to see details on this item	3.6.1.19Name: nucleoside-triphosphate diphosphatase Other names: nucleoside-triphosphate pyrophosphatase click to see details on this item 3.6.1.23Name: dUTP diphosphatase Other names: deoxyuridine-triphosphatase, dUTPase, dUTP pyrophosphatase, desoxyuridine 5'-triphosphate nucleotidohydrolase, desoxyuridine 5'-triphosphatase click to see details on this item	[c] : dutpName: dUTP Formula: C9H11N2O14P3 Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	dumpName: dUMP Formula: C9H11N2O8P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	hap-1 \| dut-1	Pyrimidine metabolism

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