WormFlux: mechanistic analysis of C. elegans metabolism

Pathway Overview

Name .....................................................	:	Pentose and glucuronate interconversions
Related pathway (?) The pathway found in other databases to which this pathway is related. .....................................................	:	ERROR
Number of reactions .....................................................	:	11

In WormPaths (?) If the pathway is available as a WormPaths map you will find the name and link of map here. .....................................................	:	Pentose and glucuronate interconversions

External links

KEGG

MetaCyc

Reactions (?) Click to see these reactions in the related KEGG pathway (only enzymes that are represented in kegg are highlighted).

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0053Name: UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific); beta-D-glucuronoside glucuronosohydrolase Type: Regular Location: Cytosol KEGG ID: R01383;R01478 click to see details on this item	2.4.1.17Name: glucuronosyltransferase Other names: 1-naphthol glucuronyltransferase, 1-naphthol-UDP-glucuronosyltransferase, 17beta-hydroxysteroid UDP-glucuronosyltransferase, 3alpha-hydroxysteroid UDP-glucuronosyltransferase, 4-hydroxybiphenyl UDP-glucuronosyltransferase, 4-methylumbelliferone UDP-glucuronosyltransferase, 4-nitrophenol UDP-glucuronyltransferase, 4-nitrophenol UDPGT, 17-OH steroid UDPGT, 3-OH androgenic UDPGT, bilirubin uridine diphosphoglucuronyltransferase, bilirubin UDP-glucuronosyltransferase, bilirubin monoglucuronide glucuronyltransferase, bilirubin UDPGT, bilirubin glucuronyltransferase, ciramadol UDP-glucuronyltransferase, estriol UDP-glucuronosyltransferase, estrone UDP-glucuronosyltransferase, uridine diphosphoglucuronosyltransferase, uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase, uridine diphosphoglucuronate-bilirubin glucuronosyltransferase, uridine diphosphoglucuronate-estriol glucuronosyltransferase, uridine diphosphoglucuronate-estradiol glucuronosyltransferase, uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase, uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase, uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase, uridine diphosphoglucuronosyltransferase, GT, morphine glucuronyltransferase, p-hydroxybiphenyl UDP glucuronyltransferase, p-nitrophenol UDP-glucuronosyltransferase, p-nitrophenol UDP-glucuronyltransferase, p-nitrophenylglucuronosyltransferase, p-phenylphenol glucuronyltransferase, phenyl-UDP-glucuronosyltransferase, PNP-UDPGT, UDP glucuronate-estradiol-glucuronosyltransferase, UDP glucuronosyltransferase, UDP glucuronate-estriol glucuronosyltransferase, UDP glucuronic acid transferase, UDP glucuronyltransferase, UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase, UDP-glucuronate-bilirubin glucuronyltransferase, UDP-glucuronosyltransferase, UDP-glucuronyltransferase, UDPGA transferase, UDPGA-glucuronyltransferase, UDPGT, uridine diphosphoglucuronyltransferase, uridine diphosphoglucuronate-bilirubin glucuronosyltransferase, uridine diphosphate glucuronyltransferase, uridine 5'-diphosphoglucuronyltransferase, uridine diphosphoglucuronosyltransferase click to see details on this item 3.2.1.31Name: beta-glucuronidase Other names: beta-glucuronide glucuronohydrolase glucuronidase, exo-beta-D-glucuronidase, ketodase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + udpglcurName: UDP-D-glucuronate Formula: C15H19N2O18P2 Charge: -3 click to see details on this item	glcurName: D-Glucuronate Formula: C6H9O7 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + udpName: UDP Formula: C9H11N2O12P2 Charge: -3 click to see details on this item	(C03A7.13 \| C55H1.1 \| F10D2.8 \| F54C1.1 \| H23N18.4 \| K04A8.10 \| ugt-1 \| ugt-10 \| ugt-11 \| ugt-12 \| ugt-13 \| ugt-14 \| ugt-15 \| ugt-16 \| ugt-17 \| ugt-18 \| ugt-19 \| ugt-2 \| ugt-20 \| ugt-21 \| ugt-22 \| ugt-23 \| ugt-24 \| ugt-25 \| ugt-26 \| ugt-27 \| ugt-29 \| ugt-3 \| ugt-30 \| ugt-31 \| ugt-32 \| ugt-33 \| ugt-34 \| ugt-35 \| ugt-36 \| ugt-37 \| ugt-38 \| ugt-39 \| ugt-4 \| ugt-40 \| ugt-41 \| ugt-42 \| ugt-43 \| ugt-44 \| ugt-45 \| ugt-46 \| ugt-47 \| ugt-48 \| ugt-49 \| ugt-5 \| ugt-50 \| ugt-51 \| ugt-52 \| ugt-53 \| ugt-54 \| ugt-55 \| ugt-56 \| ugt-58 \| ugt-59 \| ugt-6 \| ugt-60 \| ugt-61 \| ugt-62 \| ugt-63 \| ugt-64 \| ugt-65 \| ugt-7 \| ugt-8 \| ugt-9) & (Y105E8B.9)	Pentose and glucuronate interconversions
RC01904Name: Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) Type: Regular Location: Cytosol KEGG ID: R01904 click to see details on this item	1.1.1.10Name: L-xylulose reductase Other names: xylitol dehydrogenase (ambiguous) click to see details on this item	[c] : hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + xylu-LName: L-Xylulose Formula: C5H10O5 Charge: 0 click to see details on this item	nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + xyltName: Xylitol Formula: C5H12O5 Charge: 0 click to see details on this item	dhs-21	Pentose and glucuronate interconversions
RC01431Name: xylitol:NADP+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01431 click to see details on this item	1.1.1.21Name: aldehyde reductase Other names: aldose reductase, polyol dehydrogenase (NADP+), ALR2, alditol:NADP+ oxidoreductase, alditol:NADP+ 1-oxidoreductase, NADPH-aldopentose reductase, NADPH-aldose reductase click to see details on this item	[c] : hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + xyl-DName: D-Xylose Formula: C5H10O5 Charge: 0 click to see details on this item	nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + xyltName: Xylitol Formula: C5H12O5 Charge: 0 click to see details on this item	Y39G8B.1	Pentose and glucuronate interconversions
RC01758Name: L-Arabitol:NAD+ 1-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01758 click to see details on this item	1.1.1.21Name: aldehyde reductase Other names: aldose reductase, polyol dehydrogenase (NADP+), ALR2, alditol:NADP+ oxidoreductase, alditol:NADP+ 1-oxidoreductase, NADPH-aldopentose reductase, NADPH-aldose reductase click to see details on this item	[c] : arab-LName: L-Arabinose Formula: C5H10O5 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	abtName: L-Arabinitol Formula: C5H12O5 Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	Y39G8B.1	Pentose and glucuronate interconversions
RC01759Name: L-Arabitol:NADP+ 1-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01759 click to see details on this item	1.1.1.21Name: aldehyde reductase Other names: aldose reductase, polyol dehydrogenase (NADP+), ALR2, alditol:NADP+ oxidoreductase, alditol:NADP+ 1-oxidoreductase, NADPH-aldopentose reductase, NADPH-aldose reductase click to see details on this item	[c] : arab-LName: L-Arabinose Formula: C5H10O5 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item	abtName: L-Arabinitol Formula: C5H12O5 Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	Y39G8B.1	Pentose and glucuronate interconversions
RC01639Name: ATP:D-xylulose 5-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01639 click to see details on this item	2.7.1.17Name: xylulokinase Other names: xylulokinase (phosphorylating), D-xylulokinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + xylu-DName: D-Xylulose Formula: C5H10O5 Charge: 0 click to see details on this item	adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + xu5p-DName: D-Xylulose 5-phosphate Formula: C5H9O8P Charge: -2 click to see details on this item	R08D7.7	Pentose and glucuronate interconversions
RC02640Name: L-Gulonate:NAD+ 3-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02640 click to see details on this item	1.1.1.45Name: L-gulonate 3-dehydrogenase Other names: L-3-aldonate dehydrogenase, L-3-aldonic dehydrogenase, L-gulonic acid dehydrogenase, L-beta-hydroxyacid dehydrogenase, L-beta-hydroxy-acid-NAD+-oxidoreductase, L-3-hydroxyacid dehydrogenase click to see details on this item	[c] : gulnName: L-Gulonate Formula: C6H11O7 Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	3dhgulnName: 3-Dehydro-L-gulonate Formula: C6H9O7 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	[(Y71F9B.9)]	Pentose and glucuronate interconversions
RC01896Name: xylitol dehydrogenase (D-xyulose-forming) Type: Regular Location: Cytosol KEGG ID: R01896 click to see details on this item	1.1.1.14Name: L-iditol 2-dehydrogenase Other names: polyol dehydrogenase, sorbitol dehydrogenase, L-iditol:NAD+ 5-oxidoreductase, L-iditol (sorbitol) dehydrogenase, glucitol dehydrogenase, L-iditol:NAD+ oxidoreductase, NAD+-dependent sorbitol dehydrogenase, NAD+-sorbitol dehydrogenase click to see details on this item	[c] : nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + xyltName: Xylitol Formula: C5H12O5 Charge: 0 click to see details on this item	hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + xylu-DName: D-Xylulose Formula: C5H10O5 Charge: 0 click to see details on this item	R04B5.5 \| R04B5.6	Pentose and glucuronate interconversions
RC01903Name: L-arabinitol 4-dehydrogenase Type: Regular Location: Cytosol KEGG ID: R01903 click to see details on this item	1.1.1.12Name: L-arabinitol 4-dehydrogenase Other names: pentitol-DPN dehydrogenase (ambiguous), L-arabitol dehydrogenase click to see details on this item	[c] : abtName: L-Arabinitol Formula: C5H12O5 Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + xylu-LName: L-Xylulose Formula: C5H10O5 Charge: 0 click to see details on this item	Unknown	Pentose and glucuronate interconversions
RC01905Name: dehydro-L-gulonate decarboxylase Type: Regular Location: Cytosol KEGG ID: R01905 click to see details on this item	4.1.1.34Name: dehydro-L-gulonate decarboxylase Other names: keto-L-gulonate decarboxylase, 3-keto-L-gulonate decarboxylase, 3-dehydro-L-gulonate carboxy-lyase click to see details on this item	[c] : 3dhgulnName: 3-Dehydro-L-gulonate Formula: C6H9O7 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + xylu-LName: L-Xylulose Formula: C5H10O5 Charge: 0 click to see details on this item	Unknown	Pentose and glucuronate interconversions
RC01481Name: gulonate dehydrogenase, endoplasmic reticulum Type: Regular Location: Cytosol KEGG ID: R01481 click to see details on this item	1.1.1.19Name: glucuronate reductase Other names: aldehyde reductase, L-hexonate:NADP dehydrogenase, TPN-L-gulonate dehydrogenase, aldehyde reductase II, NADP-L-gulonate dehydrogenase, D-glucuronate dehydrogenase, D-glucuronate reductase, L-glucuronate reductase (incorrect) click to see details on this item	[c] : glcurName: D-Glucuronate Formula: C6H9O7 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item	gulnName: L-Gulonate Formula: C6H11O7 Charge: -1 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	Unknown	Pentose and glucuronate interconversions

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