Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	cbl1
Name .....................................................	:	Cob(I)alamin, etc.Cbl, Vitamin B12s
Model ID .....................................................	:	C00853
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00853
Formula .....................................................	:	C62H88CoN13O14P
Charge .....................................................	:	-1
Localization .....................................................	:	Extracellular, Cytosol, Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	cbl1
Other associations .....................................................	:	See reaction table below (7 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Not yet represented in WormPaths maps.

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM01492Name: ATP:cob(I)alamin Co-beta-adenosyltransferase Type: Regular Location: Mitochondria KEGG ID: R01492 click to see details on this item	2.5.1.17Name: cob(I)yrinic acid a,c-diamide adenosyltransferase Other names: CobA, CobO, ATP:corrinoid adenosyltransferase, cob(I)alamin adenosyltransferase, aquacob(I)alamin adenosyltransferase, aquocob(I)alamin vitamin B12s adenosyltransferase, ATP:cob(I)alamin Cobeta-adenosyltransferase click to see details on this item	[m] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		adocblName: Adenosylcobalamin Formula: C72H100CoN18O17P Charge: 0 click to see details on this item + pppiName: Inorganic triphosphate Formula: HO10P3 Charge: -4 click to see details on this item	mmab-1 | Y76A2B.5	Miscellaneous
DGR0006Name: Bacterial soluble pool composition Type: Degradation Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	[e] : soluble_BACName: Soluble pool in bacterial diet Formula: X Charge: 0 click to see details on this item		(0.00625) mobdName: Molybdate Formula: MoO4 Charge: -2 click to see details on this item + (0.0002) q8Name: Ubiquinone-8 Formula: C49H74O4 Charge: 0 click to see details on this item + (0.0002) thmName: Thiamin Formula: C12H17N4OS Charge: 1 click to see details on this item + (0.000903) thmppName: Thiamine diphosphate Formula: C12H16N4O7P2S Charge: -2 click to see details on this item + (0.0002) adocblName: Adenosylcobalamin Formula: C72H100CoN18O17P Charge: 0 click to see details on this item + (0.0002) selcysName: Selenocysteine Formula: C3H7NO2Se Charge: 0 click to see details on this item + (0.0002) cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item + (0.000443) ribflvName: Riboflavin Formula: C17H20N4O6 Charge: 0 click to see details on this item + (0.0002) phemeName: Protoheme Formula: C34H30FeN4O4 Charge: 0 click to see details on this item + (0.0002) pydxnName: Pyridoxine Formula: C8H11NO3 Charge: 0 click to see details on this item + (0.000893) fe2Name: Fe2+ Formula: Fe Charge: 2 click to see details on this item + (0.0002) pydamName: Pyridoxamine Formula: C8H13N2O2 Charge: 1 click to see details on this item + (0.001172) fmnName: FMN Formula: C17H19N4O9P Charge: -2 click to see details on this item + (0.0002) folName: Folate Formula: C19H18N7O6 Charge: -1 click to see details on this item + (0.004018) acornName: N2-Acetyl-L-ornithine Formula: C7H14N2O3 Charge: 0 click to see details on this item + (0.0002) pnto-RName: (R)-Pantothenate Formula: C9H16NO5 Charge: -1 click to see details on this item + (0.002774) fadName: Flavin adenine dinucleotide oxidized Formula: C27H31N9O15P2 Charge: -2 click to see details on this item + (0.0002) pydxName: Pyridoxal Formula: C8H9NO3 Charge: 0 click to see details on this item + (0.0002) tmaName: trimethylamine Formula: C3H10N Charge: 1 click to see details on this item + (0.0002) acserName: O-Acetyl-L-serine Formula: C5H9NO4 Charge: 0 click to see details on this item	Not applicable	Bacterial digestion
DMN0086Name: vitamin B12 demand (cbl1 form) Type: Demand Location: Mitochondria KEGG ID: NA click to see details on this item	Not applicable	cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item[m]			Not applicable	Demand reactions
TCE5004Name: cobalamin transport into cytosol Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c] + cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item[e] + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item[c]		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[c] + cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item[c] + hName: H+ Formula: H Charge: 1 click to see details on this item[c] + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item[c]	To be determined	Transport
TCM5005Name: cobalamin transport into mitochondria Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item[c]		cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item[m]	Not determined	Transport
TCE5105Name: Secretion of cobalamin Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c] + cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item[c] + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item[c]		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[c] + cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item[e] + hName: H+ Formula: H Charge: 1 click to see details on this item[c] + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item[c]	mrp-5	Transport
EX00853Name: cobalamin exchange/defecation Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	cbl1Name: Cob(I)alamin Formula: C62H88CoN13O14P Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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