Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

Metabolite Overview

Abbreviation .....................................................	:	akg
Name .....................................................	:	2-Oxoglutarate, etc.Oxoglutaric acid, 2-Ketoglutaric acid, alpha-Ketoglutaric acid
Model ID .....................................................	:	C00026
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00026
Formula .....................................................	:	C5H4O5
Charge .....................................................	:	-2
Localization .....................................................	:	Extracellular, Cytosol, Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	akg
Other associations .....................................................	:	See reaction table below (50 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Represented in 21 maps... Alanine metabolism (m) Arginine metabolism (m) Ascaroside biosynthesis (c) Aspartate and asparagine metabolism (c,m) Collagen biosynthesis (c) Cysteine metabolism (c,m) Glutamate / glutamine metabolism (c,m) Isoleucine degradation (m) Ketone body metabolism (m) Leucine degradation (m) Lysine degradation (m) Methionine salvage (c) Phenylalanine degradation (c) Proline metabolism (c,m) Propionate degradation (m) Serine metabolism (c) TCA cycle (c,m) Tryptophan degradation (c) Tyrosine metabolism (c,m) Ubiquinone metabolism (c,m) Valine degradation (m)   Go to map

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00093Name: L-Glutamate:NAD+ oxidoreductase (transaminating) Type: Regular Location: Cytosol KEGG ID: R00093 click to see details on this item	1.4.1.14Name: glutamate synthase (NADH) Other names: glutamate (reduced nicotinamide adenine dinucleotide) synthase, NADH: GOGAT, L-glutamate synthase (NADH), L-glutamate synthetase, NADH-glutamate synthase, NADH-dependent glutamate synthase, glutamate synthase (NADH) click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + gln-LName: L-Glutamine Formula: C5H10N2O3 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item		(2) glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	W07E11.1	Glutamate / glutamine metabolism
RM00243Name: L-glutamate:NAD+ oxidoreductase (deaminating) Type: Regular Location: Mitochondria KEGG ID: R00243 click to see details on this item	1.4.1.3Name: glutamate dehydrogenase [NAD(P)+] Other names: glutamic dehydrogenase, glutamate dehydrogenase [NAD(P)+] click to see details on this item	[m] : glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	gdh-1	Glutamate / glutamine metabolism
RM00248Name: L-Glutamate:NADP+ oxidoreductase (deaminating) Type: Regular Location: Mitochondria KEGG ID: R00248 click to see details on this item	1.4.1.3Name: glutamate dehydrogenase [NAD(P)+] Other names: glutamic dehydrogenase, glutamate dehydrogenase [NAD(P)+] click to see details on this item 1.4.1.13Name: glutamate synthase (NADPH) Other names: glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase, L-glutamate synthase, L-glutamate synthetase, glutamate synthetase (NADP), NADPH-dependent glutamate synthase, glutamine-ketoglutaric aminotransferase, NADPH-glutamate synthase, NADPH-linked glutamate synthase, glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP), L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing, GOGAT click to see details on this item	[m] : glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	gdh-1	Glutamate / glutamine metabolism
RM00355Name: L-Aspartate:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R00355 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + asp-LName: L-Aspartate Formula: C4H6NO4 Charge: -1 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + oaaName: Oxaloacetate Formula: C4H2O5 Charge: -2 click to see details on this item	got-2.1 | got-2.2	Aspartate and asparagine metabolism
RC00355Name: L-Aspartate:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R00355 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + asp-LName: L-Aspartate Formula: C4H6NO4 Charge: -1 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + oaaName: Oxaloacetate Formula: C4H2O5 Charge: -2 click to see details on this item	got-1.2	Aspartate and asparagine metabolism
RM01648Name: 4-aminobutanoate:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R01648 click to see details on this item	2.6.1.19Name: 4-aminobutyrate---2-oxoglutarate transaminase Other names: beta-alanine-oxoglutarate transaminase, aminobutyrate aminotransferase (ambiguous), beta-alanine aminotransferase, beta-alanine-oxoglutarate aminotransferase, gamma-aminobutyrate aminotransaminase (ambiguous), gamma-aminobutyrate transaminase (ambiguous), gamma-aminobutyrate-alpha-ketoglutarate aminotransferase, gamma-aminobutyrate-alpha-ketoglutarate transaminase, gamma-aminobutyrate:alpha-oxoglutarate aminotransferase, gamma-aminobutyric acid aminotransferase (ambiguous), gamma-aminobutyric acid transaminase (ambiguous), gamma-aminobutyric acid-alpha-ketoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase, gamma-aminobutyric acid-2-oxoglutarate transaminase, gamma-aminobutyric transaminase (ambiguous), 4-aminobutyrate aminotransferase (ambiguous), 4-aminobutyrate-2-ketoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate transaminase, 4-aminobutyric acid 2-ketoglutaric acid aminotransferase, 4-aminobutyric acid aminotransferase (ambiguous), aminobutyrate transaminase (ambiguous), GABA aminotransferase (ambiguous), GABA transaminase (ambiguous), GABA transferase, GABA-alpha-ketoglutarate aminotransferase, GABA-alpha-ketoglutarate transaminase, GABA-alpha-ketoglutaric acid transaminase, GABA-alpha-oxoglutarate aminotransferase, GABA-2-oxoglutarate aminotransferase, GABA-2-oxoglutarate transaminase, GABA-oxoglutarate aminotransferase, GABA-oxoglutarate transaminase, glutamate-succinic semialdehyde transaminase, GabT click to see details on this item	[m] : 4abutName: 4-Aminobutanoate Formula: C4H9NO2 Charge: 0 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + sucsalName: Succinic semialdehyde Formula: C4H5O3 Charge: -1 click to see details on this item	gta-1	Glutamate / glutamine metabolism
RM00258Name: L-Alanine:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R00258 click to see details on this item	2.6.1.2Name: alanine transaminase Other names: glutamic-pyruvic transaminase, glutamic-alanine transaminase, GPT (ambiguous), beta-alanine aminotransferase, alanine aminotransferase, alanine-alpha-ketoglutarate aminotransferase, alanine-pyruvate aminotransferase, ALT, glutamic acid-pyruvic acid transaminase, glutamic-pyruvic aminotransferase, L-alanine aminotransferase, L-alanine transaminase, L-alanine-alpha-ketoglutarate aminotransferase, pyruvate transaminase, pyruvate-alanine aminotransferase, pyruvate-glutamate transaminase click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + ala-LName: L-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item	C32F10.8	Alanine metabolism
RM00667Name: L-Ornithine:2-oxo-acid aminotransferase Type: Regular Location: Mitochondria KEGG ID: R00667 click to see details on this item	2.6.1.13Name: ornithine aminotransferase Other names: ornithine delta-transaminase, L-ornithine:alpha-ketoglutarate delta-aminotransferase, OAT, L-ornithine 5-aminotransferase, L-ornithine aminotransferase, ornithine 5-aminotransferase, ornithine transaminase, ornithine-alpha-ketoglutarate aminotransferase, ornithine-2-oxoacid aminotransferase, ornithine-keto acid aminotransferase, ornithine-keto acid transaminase, ornithine-ketoglutarate aminotransferase, ornithine-oxo acid aminotransferase, ornithine:alpha-oxoglutarate transaminase, ornithine---oxo-acid transaminase click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + ornName: Ornithine Formula: C5H13N2O2 Charge: 1 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + glu5saName: L-Glutamate 5-semialdehyde Formula: C5H9NO3 Charge: 0 click to see details on this item	oatr-1	Arginine metabolism
RC01252Name: L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) Type: Regular Location: Cytosol KEGG ID: R01252 click to see details on this item	1.14.11.2Name: procollagen-proline dioxygenase Other names: protocollagen hydroxylase, proline hydroxylase, proline,2-oxoglutarate 4-dioxygenase, collagen proline hydroxylase, hydroxylase, collagen proline, peptidyl proline hydroxylase, proline protocollagen hydroxylase, proline, 2-oxoglutarate dioxygenase, prolyl hydroxylase, prolylprotocollagen dioxygenase, prolylprotocollagen hydroxylase, protocollagen proline 4-hydroxylase, protocollagen proline dioxygenase, protocollagen proline hydroxylase, protocollagen prolyl hydroxylase, prolyl 4-hydroxylase, prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating, procollagen-proline 4-dioxygenase click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + pro-LName: L-Proline Formula: C5H9NO2 Charge: 0 click to see details on this item		4hpro-LTName: trans-4-Hydroxy-L-proline Formula: C5H9NO3 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item	C14E2.4 | Y43F8B.19 | dpy-18 | phy-2 | phy-3 | phy-4	Proline metabolism
RM05052Name: L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R05052 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + e4hgluName: L-erythro-4-Hydroxyglutamate Formula: C5H8NO5 Charge: -1 click to see details on this item		4h2ogltName: 4-Hydroxy-2-oxoglutarate Formula: C5H4O6 Charge: -2 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-2.1 | got-2.2	Proline metabolism
RC05052Name: L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R05052 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + e4hgluName: L-erythro-4-Hydroxyglutamate Formula: C5H8NO5 Charge: -1 click to see details on this item		4h2ogltName: 4-Hydroxy-2-oxoglutarate Formula: C5H4O6 Charge: -2 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-1.2	Proline metabolism
RCC0211Name: very long chain ascaroside (w-ascr-C27) synthesis Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	[c] : fa28p0coaName: octacosanoyl-CoA Formula: C49H86N7O17P3S Charge: -4 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + (2) o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + cdpasclName: CDP-ascarylose Formula: C15H23N3O14P2 Charge: -2 click to see details on this item		27ascfa27p0coaName: 27-ascaryl-heptacosanoic acyl coa Formula: C54H94N7O21P3S Charge: -4 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (3) hName: H+ Formula: H Charge: 1 click to see details on this item + ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + cdpName: CDP Formula: C9H12N3O11P2 Charge: -3 click to see details on this item + forName: Formate Formula: CH1O2 Charge: -1 click to see details on this item	Unknown	Ascaroside biosynthesis
RM03534Name: 2-Hydroxyglutarate:(acceptor) 2-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03534;R10575 click to see details on this item	1.1.99.2Name: L-2-hydroxyglutarate dehydrogenase Other names: alpha-ketoglutarate reductase, alpha-hydroxyglutarate dehydrogenase, L-alpha-hydroxyglutarate dehydrogenase, hydroxyglutaric dehydrogenase, alpha-hydroxyglutarate oxidoreductase, L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase, alpha-hydroxyglutarate dehydrogenase (NAD+ specific), (S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase click to see details on this item 1.1.99.39Name: D-2-hydroxyglutarate dehydrogenase Other names: AtD-2HGDH click to see details on this item	[m] : 2hglutName: (S)-2-Hydroxyglutarate Formula: C5H6O5 Charge: -2 click to see details on this item + fadName: Flavin adenine dinucleotide oxidized Formula: C27H31N9O15P2 Charge: -2 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + fadh2Name: Flavin adenine dinucleotide reduced Formula: C27H33N9O15P2 Charge: -2 click to see details on this item	Y45G12B.3 | F54D5.12	Miscellaneous
RC08198Name: alphaKG reductase Type: Regular Location: Cytosol KEGG ID: R08198 click to see details on this item	1.1.1.95Name: phosphoglycerate dehydrogenase Other names: D-3-phosphoglycerate:NAD+ oxidoreductase, alpha-phosphoglycerate dehydrogenase, 3-phosphoglycerate dehydrogenase, 3-phosphoglyceric acid dehydrogenase, D-3-phosphoglycerate dehydrogenase, glycerate 3-phosphate dehydrogenase, glycerate-1,3-phosphate dehydrogenase, phosphoglycerate oxidoreductase, phosphoglyceric acid dehydrogenase, SerA, 3-phosphoglycerate:NAD+ 2-oxidoreductase, SerA 3PG dehydrogenase, 3PHP reductase, alphaKG reductase, D- and L-HGA click to see details on this item	[c] : 2hglutName: (S)-2-Hydroxyglutarate Formula: C5H6O5 Charge: -2 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	C31C9.2	Miscellaneous
RM03225Name: (S)-3-Hydroxybutanoate:2-oxoglutarate oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03225 click to see details on this item	1.1.99.24Name: hydroxyacid-oxoacid transhydrogenase Other names: transhydrogenase, hydroxy acid-oxo acid click to see details on this item	[m] : S3hbName: (S)-3-Hydroxybutanoate Formula: C4H7O3 Charge: -1 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item		acacName: Acetoacetate Formula: C4H5O3 Charge: -1 click to see details on this item + 2hglutName: (S)-2-Hydroxyglutarate Formula: C5H6O5 Charge: -2 click to see details on this item	hphd-1	Ketone body metabolism
RC02397Name: 4-Trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) Type: Regular Location: Cytosol KEGG ID: R02397 click to see details on this item	1.14.11.1Name: gamma-butyrobetaine dioxygenase Other names: alpha-butyrobetaine hydroxylase, gamma-butyrobetaine hydroxylase, butyrobetaine hydroxylase click to see details on this item	[c] : 4tmeabutnName: 4-Trimethylammoniobutanoate Formula: C7H15NO2 Charge: 0 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + crnName: L-Carnitine Formula: C7H15NO3 Charge: 0 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item	gbh-1	Carnitine biosynthesis
RM03451Name: trimethyllysine dioxygenase Type: Regular Location: Mitochondria KEGG ID: R03451 click to see details on this item	1.14.11.8Name: trimethyllysine dioxygenase Other names: trimethyllysine alpha-ketoglutarate dioxygenase, TML-alpha-ketoglutarate dioxygenase, TML hydroxylase, 6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + tmlysName: N6,N6,N6-Trimethyl-L-lysine Formula: C9H21N2O2 Charge: 1 click to see details on this item		3htmelysName: 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine Formula: C9H21N2O3 Charge: 1 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item	gbh-2	Carnitine biosynthesis
RC00267Name: Isocitrate:NADP+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00267 click to see details on this item	1.1.1.42Name: isocitrate dehydrogenase (NADP+) Other names: oxalosuccinate decarboxylase, oxalsuccinic decarboxylase, isocitrate (NADP) dehydrogenase, isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase, NADP-specific isocitrate dehydrogenase, NADP-linked isocitrate dehydrogenase, NADP-dependent isocitrate dehydrogenase, NADP isocitric dehydrogenase, isocitrate dehydrogenase (NADP-dependent), NADP-dependent isocitric dehydrogenase, triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase, NADP+-linked isocitrate dehydrogenase, IDH (ambiguous), dual-cofactor-specific isocitrate dehydrogenase, NADP+-ICDH, NADP+-IDH, IDP, IDP1, IDP2, IDP3 click to see details on this item	[c] : icitName: Isocitrate Formula: C6H5O7 Charge: -3 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item	idh-1	TCA cycle
RM00267Name: Isocitrate:NADP+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R00267 click to see details on this item	1.1.1.42Name: isocitrate dehydrogenase (NADP+) Other names: oxalosuccinate decarboxylase, oxalsuccinic decarboxylase, isocitrate (NADP) dehydrogenase, isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase, NADP-specific isocitrate dehydrogenase, NADP-linked isocitrate dehydrogenase, NADP-dependent isocitrate dehydrogenase, NADP isocitric dehydrogenase, isocitrate dehydrogenase (NADP-dependent), NADP-dependent isocitric dehydrogenase, triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase, NADP+-linked isocitrate dehydrogenase, IDH (ambiguous), dual-cofactor-specific isocitrate dehydrogenase, NADP+-ICDH, NADP+-IDH, IDP, IDP1, IDP2, IDP3 click to see details on this item	[m] : icitName: Isocitrate Formula: C6H5O7 Charge: -3 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item	idh-1 | idh-2	TCA cycle
RM00709Name: Isocitrate:NAD+ oxidoreductase (decarboxylating) Type: Regular Location: Mitochondria KEGG ID: R00709 click to see details on this item	1.1.1.41Name: isocitrate dehydrogenase (NAD+) Other names: isocitric dehydrogenase, beta-ketoglutaric-isocitric carboxylase, isocitric acid dehydrogenase, NAD dependent isocitrate dehydrogenase, NAD isocitrate dehydrogenase, NAD-linked isocitrate dehydrogenase, NAD-specific isocitrate dehydrogenase, NAD isocitric dehydrogenase, isocitrate dehydrogenase (NAD), IDH (ambiguous), nicotinamide adenine dinucleotide isocitrate dehydrogenase click to see details on this item	[m] : icitName: Isocitrate Formula: C6H5O7 Charge: -3 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	idha-1 & idhb-1 & (idhg-1 | idhg-2)	TCA cycle
RMC0003Name: 2-oxoglutarate dehydrogenase Type: Regular Location: Mitochondria KEGG ID: R00621;R03316;R02570;R07618 click to see details on this item	1.2.4.2Name: oxoglutarate dehydrogenase (succinyl-transferring) Other names: 2-ketoglutarate dehydrogenase, 2-oxoglutarate dehydrogenase, 2-oxoglutarate: lipoate oxidoreductase, 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating), alpha-ketoglutarate dehydrogenase, alphaketoglutaric acid dehydrogenase, alpha-ketoglutaric dehydrogenase, alpha-oxoglutarate dehydrogenase, AKGDH, OGDC, ketoglutaric dehydrogenase, oxoglutarate decarboxylase, oxoglutarate dehydrogenase, oxoglutarate dehydrogenase (lipoamide) click to see details on this item 2.3.1.61Name: dihydrolipoyllysine-residue succinyltransferase Other names: dihydrolipoamide S-succinyltransferase, dihydrolipoamide succinyltransferase, dihydrolipoic transsuccinylase, dihydrolipolyl transsuccinylase, dihydrolipoyl transsuccinylase, lipoate succinyltransferase (Escherichia coli), lipoic transsuccinylase, lipoyl transsuccinylase, succinyl-CoA:dihydrolipoamide S-succinyltransferase, succinyl-CoA:dihydrolipoate S-succinyltransferase, enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase click to see details on this item 1.8.1.4Name: dihydrolipoyl dehydrogenase Other names: LDP-Glc, LDP-Val, dehydrolipoate dehydrogenase, diaphorase, dihydrolipoamide dehydrogenase, dihydrolipoamide:NAD+ oxidoreductase, dihydrolipoic dehydrogenase, dihydrothioctic dehydrogenase, lipoamide dehydrogenase (NADH), lipoamide oxidoreductase (NADH), lipoamide reductase, lipoamide reductase (NADH), lipoate dehydrogenase, lipoic acid dehydrogenase, lipoyl dehydrogenase, protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + succoaName: Succinyl-CoA Formula: C25H35N7O19P3S Charge: -5 click to see details on this item	(ogdh-1 & ogdh-2) & dlst-1 & dld-1	TCA cycle
RC03376Name: Protein lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating) Type: Regular Location: Cytosol KEGG ID: R03376 click to see details on this item	1.14.11.4Name: procollagen-lysine 5-dioxygenase Other names: lysine hydroxylase, lysine,2-oxoglutarate 5-dioxygenase, protocollagen lysine dioxygenase, collagen lysine hydroxylase, lysine-2-oxoglutarate dioxygenase, lysyl hydroxylase, lysylprotocollagen dioxygenase, protocollagen lysyl hydroxylase, peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase, peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase, protocollagen lysine hydroxylase, procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating) click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + pcollglysName: Procollagen L-lysine (to be modified) Formula: XH Charge: 1 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + pcollg5hlysName: Procollagen 5-hydroxy-L-lysine Formula: XHO Charge: 1 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item	let-268	Collagen biosynthesis
RC03219Name: Procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) Type: Regular Location: Cytosol KEGG ID: R03219 click to see details on this item	1.14.11.2Name: procollagen-proline dioxygenase Other names: protocollagen hydroxylase, proline hydroxylase, proline,2-oxoglutarate 4-dioxygenase, collagen proline hydroxylase, hydroxylase, collagen proline, peptidyl proline hydroxylase, proline protocollagen hydroxylase, proline, 2-oxoglutarate dioxygenase, prolyl hydroxylase, prolylprotocollagen dioxygenase, prolylprotocollagen hydroxylase, protocollagen proline 4-hydroxylase, protocollagen proline dioxygenase, protocollagen proline hydroxylase, protocollagen prolyl hydroxylase, prolyl 4-hydroxylase, prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating, procollagen-proline 4-dioxygenase click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + pcollgproName: Procollagen L-proline (to be modified) Formula: XH Charge: 0 click to see details on this item		pcollg4hproName: Procollagen trans-4-hydroxy-L-proline Formula: XOH Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item	C14E2.4 | Y43F8B.19 | dpy-18 | phy-2 | phy-3 | phy-4	Collagen biosynthesis
RM02433Name: L-cysteate:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R02433 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item	[m] : LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item		3spyrName: 3-Sulfopyruvate Formula: C3H2O6S Charge: -2 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-2.1 | got-2.2	Cysteine metabolism
RC02619Name: 3-sulfino-L-alanine:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R02619 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item	[c] : 3salaName: 3-Sulfino-L-alanine Formula: C3H5NO4S Charge: -2 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		3snpyrName: 3-Sulfinopyruvate Formula: C3H2O5S Charge: -2 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-1.2	Cysteine metabolism
RM02619Name: 3-sulfino-L-alanine:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R02619 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item	[m] : 3salaName: 3-Sulfino-L-alanine Formula: C3H5NO4S Charge: -2 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		3snpyrName: 3-Sulfinopyruvate Formula: C3H2O5S Charge: -2 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-2.1 | got-2.2	Cysteine metabolism
RC07396Name: 2-keto-4-methylthiobutyrate transamination Type: Regular Location: Cytosol KEGG ID: R07396 click to see details on this item	2.6.1.5Name: tyrosine transaminase Other names: tyrosine aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, glutamic phenylpyruvic aminotransferase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, tyrosine-2-ketoglutarate aminotransferase, TyrAT click to see details on this item	[c] : 2kmbName: 2-keto-4-methylthiobutyrate Formula: C5H7O3S Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + met-LName: L-Methionine Formula: C5H11NO2S Charge: 0 click to see details on this item	tatn-1	Methionine salvage
RC00895Name: L-Cysteine:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R00895 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item	[c] : cys-LName: L-Cysteine Formula: C3H7NO2S Charge: 0 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item		mercppyrName: Mercaptopyruvate Formula: C3H3O3S Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-1.2 | got-2.1 | got-2.2	Cysteine metabolism
RC04173Name: 3-Phosphoserine:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R04173 click to see details on this item	2.6.1.52Name: phosphoserine transaminase Other names: PSAT, phosphoserine aminotransferase, 3-phosphoserine aminotransferase, hydroxypyruvic phosphate-glutamic transaminase, L-phosphoserine aminotransferase, phosphohydroxypyruvate transaminase, phosphohydroxypyruvic-glutamic transaminase, 3-O-phospho-L-serine:2-oxoglutarate aminotransferase, SerC, PdxC, 3PHP transaminase click to see details on this item	[c] : 3phpName: 3-Phosphohydroxypyruvate Formula: C3H2O7P Charge: -3 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + pser-LName: O-Phospho-L-serine Formula: C3H6NO6P Charge: -2 click to see details on this item	F26H9.5	Serine metabolism
RC09510Name: protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase Type: Regular Location: Cytosol KEGG ID: R09510 click to see details on this item	1.14.11.27Name: [histone-H3]-lysine-36 demethylase Other names: JHDM1A, JmjC domain-containing histone demethylase 1A, H3-K36-specific demethylase, histone-lysine (H3-K36) demethylase, histone demethylase, protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase click to see details on this item	[c] : NdmelysName: Histone N6,N6-dimethyl-L-lysine Formula: XC8H17N2O Charge: 1 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		NmelysName: Histone N6-methyl-L-lysine Formula: XC7H15N2O Charge: 1 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item + faldName: Formaldehyde Formula: CH2O Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	jhdm-1	Histone modification
RC09511Name: protein-N6-methyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase Type: Regular Location: Cytosol KEGG ID: R09511 click to see details on this item	1.14.11.27Name: [histone-H3]-lysine-36 demethylase Other names: JHDM1A, JmjC domain-containing histone demethylase 1A, H3-K36-specific demethylase, histone-lysine (H3-K36) demethylase, histone demethylase, protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase click to see details on this item	[c] : NmelysName: Histone N6-methyl-L-lysine Formula: XC7H15N2O Charge: 1 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		NlysName: Histone-L-Lysine Formula: XC6H13N2O Charge: 1 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item + faldName: Formaldehyde Formula: CH2O Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	jhdm-1	Histone modification
RM00716Name: N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming) Type: Regular Location: Mitochondria KEGG ID: R00716 click to see details on this item	1.5.1.8Name: saccharopine dehydrogenase (NADP+, L-lysine-forming) Other names: lysine-2-oxoglutarate reductase, lysine-ketoglutarate reductase, L-lysine-alpha-ketoglutarate reductase, lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming), saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase, 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming) click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + lys-LName: L-Lysine Formula: C6H15N2O2 Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + saccrp-LName: L-Saccharopine Formula: C11H19N2O6 Charge: -1 click to see details on this item	R02D3.1	Lysine degradation
RM01939Name: L-2-aminoadipate:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R01939 click to see details on this item	2.6.1.39Name: 2-aminoadipate transaminase Other names: alpha-aminoadipate aminotransferase, 2-aminoadipate aminotransferase, 2-aminoadipic aminotransferase, glutamic-ketoadipic transaminase, glutamate-alpha-ketoadipate transaminase click to see details on this item	[m] : L2aadpName: L-2-Aminoadipate Formula: C6H10NO4 Charge: -1 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item		2oxoadpName: 2-Oxoadipate Formula: C6H6O5 Charge: -2 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	To be determined	Lysine degradation
RC00694Name: L-Phenylalanine:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R00694 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item 2.6.1.5Name: tyrosine transaminase Other names: tyrosine aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, glutamic phenylpyruvic aminotransferase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, tyrosine-2-ketoglutarate aminotransferase, TyrAT click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + phe-LName: L-Phenylalanine Formula: C9H11NO2 Charge: 0 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + phpyrName: Phenylpyruvate Formula: C9H7O3 Charge: -1 click to see details on this item	got-1.2 | tatn-1	Phenylalanine degradation
RM00908Name: beta-alanine:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R00908 click to see details on this item	2.6.1.19Name: 4-aminobutyrate---2-oxoglutarate transaminase Other names: beta-alanine-oxoglutarate transaminase, aminobutyrate aminotransferase (ambiguous), beta-alanine aminotransferase, beta-alanine-oxoglutarate aminotransferase, gamma-aminobutyrate aminotransaminase (ambiguous), gamma-aminobutyrate transaminase (ambiguous), gamma-aminobutyrate-alpha-ketoglutarate aminotransferase, gamma-aminobutyrate-alpha-ketoglutarate transaminase, gamma-aminobutyrate:alpha-oxoglutarate aminotransferase, gamma-aminobutyric acid aminotransferase (ambiguous), gamma-aminobutyric acid transaminase (ambiguous), gamma-aminobutyric acid-alpha-ketoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase, gamma-aminobutyric acid-2-oxoglutarate transaminase, gamma-aminobutyric transaminase (ambiguous), 4-aminobutyrate aminotransferase (ambiguous), 4-aminobutyrate-2-ketoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate transaminase, 4-aminobutyric acid 2-ketoglutaric acid aminotransferase, 4-aminobutyric acid aminotransferase (ambiguous), aminobutyrate transaminase (ambiguous), GABA aminotransferase (ambiguous), GABA transaminase (ambiguous), GABA transferase, GABA-alpha-ketoglutarate aminotransferase, GABA-alpha-ketoglutarate transaminase, GABA-alpha-ketoglutaric acid transaminase, GABA-alpha-oxoglutarate aminotransferase, GABA-2-oxoglutarate aminotransferase, GABA-2-oxoglutarate transaminase, GABA-oxoglutarate aminotransferase, GABA-oxoglutarate transaminase, glutamate-succinic semialdehyde transaminase, GabT click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + msaName: Malonate semialdehyde Formula: C3H3O3 Charge: -1 click to see details on this item	gta-1	Propionate degradation
RC04073Name: Peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) Type: Regular Location: Cytosol KEGG ID: R04073 click to see details on this item	1.14.11.16Name: peptide-aspartate beta-dioxygenase Other names: aspartate beta-hydroxylase, aspartylpeptide beta-dioxygenase click to see details on this item	[c] : o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + pepaspName: Peptide L-aspartate Formula: XC4H4NO3 Charge: -1 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item + pepasp3ohName: Peptide 3-hydroxy-L-aspartate Formula: XC4H4NO4 Charge: -1 click to see details on this item	K09A9.6	Miscellaneous
RCC0180Name: Peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	1.14.11.16Name: peptide-aspartate beta-dioxygenase Other names: aspartate beta-hydroxylase, aspartylpeptide beta-dioxygenase click to see details on this item	[c] : o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + pepasnName: Peptide L-asparagine Formula: XC4H6N2O2 Charge: 0 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item + pepasn3ohName: Peptide 3-hydroxy-L-asparagine Formula: XC4H6N2O3 Charge: 0 click to see details on this item	K09A9.6	Miscellaneous
RC01956Name: L-Kynurenine:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R01956 click to see details on this item	2.6.1.7Name: kynurenine---oxoglutarate transaminase Other names: kynurenine transaminase (cyclizing), kynurenine 2-oxoglutarate transaminase, kynurenine aminotransferase, L-kynurenine aminotransferase click to see details on this item	[c] : LkynrName: L-Kynurenine Formula: C10H12N2O3 Charge: 0 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item		4aphdobName: "4-(2-Aminophenyl)-2,4-dioxobutanoate" Formula: C10H8NO4 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	nkat-1	Tryptophan degradation
RC04171Name: 3-Hydroxy-L-kynurenine:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R04171 click to see details on this item	2.6.1.7Name: kynurenine---oxoglutarate transaminase Other names: kynurenine transaminase (cyclizing), kynurenine 2-oxoglutarate transaminase, kynurenine aminotransferase, L-kynurenine aminotransferase click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + hLkynrName: 3-Hydroxy-L-kynurenine Formula: C10H12N2O4 Charge: 0 click to see details on this item		42A3HP24DBName: "4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate" Formula: C10H8NO5 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	nkat-1	Tryptophan degradation
RM00734Name: L-tyrosine:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R00734 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item 2.6.1.5Name: tyrosine transaminase Other names: tyrosine aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, glutamic phenylpyruvic aminotransferase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, tyrosine-2-ketoglutarate aminotransferase, TyrAT click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + tyr-LName: L-Tyrosine Formula: C9H11NO3 Charge: 0 click to see details on this item		34hppName: 3-(4-Hydroxyphenyl)pyruvate Formula: C9H7O4 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-2.1 | got-2.2	Tyrosine metabolism
RC00734Name: L-tyrosine:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R00734 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item 2.6.1.5Name: tyrosine transaminase Other names: tyrosine aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, glutamic phenylpyruvic aminotransferase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, tyrosine-2-ketoglutarate aminotransferase, TyrAT click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + tyr-LName: L-Tyrosine Formula: C9H11NO3 Charge: 0 click to see details on this item		34hppName: 3-(4-Hydroxyphenyl)pyruvate Formula: C9H7O4 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-1.2 | tatn-1	Tyrosine metabolism
RM01090Name: L-Leucine:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R01090 click to see details on this item	2.6.1.42Name: branched-chain-amino-acid transaminase Other names: transaminase B, branched-chain amino acid aminotransferase, branched-chain amino acid-glutamate transaminase, branched-chain aminotransferase, L-branched chain amino acid aminotransferase, glutamate-branched-chain amino acid transaminase click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + leu-LName: L-Leucine Formula: C6H13NO2 Charge: 0 click to see details on this item		4mopName: 4-Methyl-2-oxopentanoate Formula: C6H9O3 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	bcat-1 | Y44A6D.5	Leucine degradation
RM01214Name: L-Valine:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R01214 click to see details on this item	2.6.1.42Name: branched-chain-amino-acid transaminase Other names: transaminase B, branched-chain amino acid aminotransferase, branched-chain amino acid-glutamate transaminase, branched-chain aminotransferase, L-branched chain amino acid aminotransferase, glutamate-branched-chain amino acid transaminase click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + val-LName: L-Valine Formula: C5H11NO2 Charge: 0 click to see details on this item		3mobName: 3-Methyl-2-oxobutanoate Formula: C5H7O3 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	bcat-1 | Y44A6D.5	Valine degradation
RM02199Name: L-Isoleucine:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R02199 click to see details on this item	2.6.1.42Name: branched-chain-amino-acid transaminase Other names: transaminase B, branched-chain amino acid aminotransferase, branched-chain amino acid-glutamate transaminase, branched-chain aminotransferase, L-branched chain amino acid aminotransferase, glutamate-branched-chain amino acid transaminase click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + ile-LName: L-Isoleucine Formula: C6H13NO2 Charge: 0 click to see details on this item		3mopName: (S)-3-Methyl-2-oxopentanoate Formula: C6H9O3 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	bcat-1 | Y44A6D.5	Isoleucine degradation
RM04188Name: L-3-amino-isobutanoate:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R04188 click to see details on this item	2.6.1.22Name: (S)-3-amino-2-methylpropionate transaminase Other names: L-3-aminoisobutyrate transaminase, beta-aminobutyric transaminase, L-3-aminoisobutyric aminotransferase, beta-aminoisobutyrate-alpha-ketoglutarate transaminase click to see details on this item	[m] : 2mopName: 2-Methyl-3-oxopropanoate Formula: C4H5O3 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item		3aibName: L-3-Amino-isobutanoate Formula: C4H9NO2 Charge: 0 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item	gta-1	Propionate degradation
TCM5510Name: 2-oxoadipate shuttle (cytosol/mitochondria) Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	2oxoadpName: 2-Oxoadipate Formula: C6H6O5 Charge: -2 click to see details on this item[c] + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item[m]		2oxoadpName: 2-Oxoadipate Formula: C6H6O5 Charge: -2 click to see details on this item[m] + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item[c]	Not determined	Transport
TCE5347Name: 2-Oxoadipate transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	2oxoadpName: 2-Oxoadipate Formula: C6H6O5 Charge: -2 click to see details on this item[c] + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item[e]		2oxoadpName: 2-Oxoadipate Formula: C6H6O5 Charge: -2 click to see details on this item[e] + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item[c]	Not determined	Transport
TCE1121Name: 2-Oxoglutarate transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item[e]		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item[c]	Not determined	Transport
TCM0109Name: 2-Oxoglutarate and L-Malate transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item[m] + mal-LName: L-Malate Formula: C4H4O5 Charge: -2 click to see details on this item[c]		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item[c] + mal-LName: L-Malate Formula: C4H4O5 Charge: -2 click to see details on this item[m]	Not determined	Transport
EX00026Name: 2-Oxoglutarate exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item[e]			Not applicable	Exchange with the environment

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